Postoperative electronic irradiation combined with brachytherapy by <sup>192</sup>Ir for keloid:an analysis of 105 patients

Zhou Hua; Yang Hongbo; Sun Hongwen; Zhao Peizhu; Zhang Rui; Deng Wen

doi:10.13406/j.cnki.cyxb.000752

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Postoperative electronic irradiation combined with brachytherapy by ¹⁹²Ir for keloid:an analysis of 105 patients

更新时间：2024-01-17

- Postoperative electronic irradiation combined with brachytherapy by ¹⁹²Ir for keloid:an analysis of 105 patients
- Journal of Chongqing Medical University Vol. 40, Issue 12, Pages: 1555-1557(2015)
- 作者机构：
  
  1. 昆明医科大学第一附属医院肿瘤放疗科
  2. 昆明医科大学第一附属医院胸外科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.000752
  CLC： R622;R730.55
- Published：2015，
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[1]周华,杨红波,孙红文,赵培珠,张瑞,邓雯.105例瘢痕疙瘩术后电子线联合~(192)Ir敷贴放疗疗效观察[J].重庆医科大学学报,2015,40(12):1555-1557.

Zhou Hua, Yang Hongbo, Sun Hongwen, et al. Postoperative electronic irradiation combined with brachytherapy by ¹⁹²Ir for keloid:an analysis of 105 patients. [J]. Journal of Chongqing Medical University 40(12):1555-1557(2015)
[1]周华,杨红波,孙红文,赵培珠,张瑞,邓雯.105例瘢痕疙瘩术后电子线联合~(192)Ir敷贴放疗疗效观察[J].重庆医科大学学报,2015,40(12):1555-1557. DOI： 10.13406/j.cnki.cyxb.000752.

Zhou Hua, Yang Hongbo, Sun Hongwen, et al. Postoperative electronic irradiation combined with brachytherapy by ¹⁹²Ir for keloid:an analysis of 105 patients. [J]. Journal of Chongqing Medical University 40(12):1555-1557(2015) DOI： 10.13406/j.cnki.cyxb.000752.

摘要

目的:观察瘢痕疙瘩术后电子线常规分割联合后程

192

Ir敷贴放射治疗瘢痕疙瘩术后切口的临床疗效。方法:将我院2003年1月至2013年12月单发性瘢痕疙瘩患者203例分为观察组（A组）105例和对照组（B组）98例

均于术后24 h内进行放射治疗

采用直线加速器4

Me V电子线行伤口局部照射。观察组（A组）每天1次

每次2 Gy

5次/周

照射总剂量为DT 10Gy/5次

以后联合192Ir敷贴放射治疗

5 Gy/次

2次/周

共2次完成

参考点总剂量为10 Gy。对照组（B组）每天1次

每次4Gy

每周5次

总剂量为DT 20 Gy/5次。临床疗效标准参考Darzi的瘢痕疙瘩疗效分级标准进行评价。结果:术后随访12个月以上

105例患者中治愈65例

显效33例

有效率93.33%（98/105）

无效病例为7例。结论:瘢痕疙瘩术后电子线常规分割联合后程

192

Ir敷贴放射治疗是治疗瘢痕疙瘩的有效方法

能有效提高治愈率

降低复发率。

Abstract

Objective:To observe the clinical efficacy of postoperative electronic irradiation combined with brachytherapy by

192

Ir for keloid. Methods:Totally 203 cases of keloid from January 2003 to December 2013 were divided into observation group（n=105

group A） and control group（n=98

group B）. Radiotherapy was given within 24 h after operation in 105 patients with keloid. The lesions were treated by 4-6 Me V-E by Varian 2 300C/D medical linear accelerator. In group A

radiotherapy was given once a day（5 times a week） with a dosage of 2 Gy each time（10 Gy for 5 times）;then electronic irradiation combined with brachytherapy by192 Ir was given twice a week（2 times in total） with a dosage of 5 Gy each time（10 Gy for 2 times）. In group B

treatment was given once a day（5times a week） with a dosage of 4 Gy each time（20 Gy 1for 5 times）. Darzi’s criteria were used to do the evaluation and statistical analysis was made using SPSS 13.0. χ

test was used and P

0.05 was considered statistical significant. Results :Postoperative follow-up lasted for 12 months or more in 105 patients

65 were cured 33 were excellent;the effective rate was 93.33%;7 cases were invalid. Conclusion:Postoperative electronic line in keloid by normal radiotherapy combined with late course

192

Ir brachytherapy is effective in improving the cure rate and reducing recurrence rate.

关键词

瘢痕疙瘩外科手术放疗敷贴治疗192Ir

Keywords

keloidsurgeryradiotherapybrachytherapy192Ir

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Department of Otolaryngology,the First Affiliated Hospital,Chongqing Medical University

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重庆医科大学附属第一医院肿瘤科

⁰

Postoperative electronic irradiation combined with brachytherapy by 192Ir for keloid:an analysis of 105 patients

DOI：10.13406/j.cnki.cyxb.000752

摘要

Abstract

关键词

Keywords

references

Postoperative electronic irradiation combined with brachytherapy by ¹⁹²Ir for keloid:an analysis of 105 patients