RNAi technology applied to the preparation of molecular probes for diagnosis and treatment of ovarian cancer

Wu Xiaofeng; Wen Ming

doi:10.13406/j.cnki.cyxb.000674

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RNAi technology applied to the preparation of molecular probes for diagnosis and treatment of ovarian cancer

更新时间：2024-01-17

- RNAi technology applied to the preparation of molecular probes for diagnosis and treatment of ovarian cancer
- Journal of Chongqing Medical University Vol. 40, Issue 12, Pages: 1491-1495(2015)
- 作者机构：
  
  重庆医科大学附属第一医院放射科
- 作者简介：
- 基金信息：
- DOI：10.13406/j.cnki.cyxb.000674
  CLC： R445.2;R737.31
- Published：2015，
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[1]吴晓凤,文明.RNAi技术应用于制备诊治卵巢癌的MR成像分子探针[J].重庆医科大学学报,2015,40(12):1491-1495.

Wu Xiaofeng, Wen Ming. RNAi technology applied to the preparation of molecular probes for diagnosis and treatment of ovarian cancer. [J]. Journal of Chongqing Medical University 40(12):1491-1495(2015)
[1]吴晓凤,文明.RNAi技术应用于制备诊治卵巢癌的MR成像分子探针[J].重庆医科大学学报,2015,40(12):1491-1495. DOI： 10.13406/j.cnki.cyxb.000674.

Wu Xiaofeng, Wen Ming. RNAi technology applied to the preparation of molecular probes for diagnosis and treatment of ovarian cancer. [J]. Journal of Chongqing Medical University 40(12):1491-1495(2015) DOI： 10.13406/j.cnki.cyxb.000674.

摘要

近年来随着分子影像学研究的深入发展

分子探针的设计、开发方面也取得了长足的进步。作为一种高效的序列特异性基因剔除技术

利用RNA干扰理论制备用于分子成像的探针

可望在对相应恶性肿瘤做出早期特异性诊断的同时

实现一体化的靶向基因治疗。本文就RNA干扰技术应用于制备诊治卵巢癌的MR分子成像探针研究做出综述。

Abstract

RNA interference(RNAi) offers great potential not only for in vitro target validation

but also as a novel therapeutic strategy based on the highly specific and efficient silencing of a target gene. The technique of RNAi could be used for preparing molecular probes

for making earlier and specific diagnosis

and for targeted gene therapy of malignant tumors.

关键词

RNA干扰卵巢癌分子探针分子影像学

Keywords

RNA interferenceovarian cancermolecular probemolecular imaging

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Related Institution

Department of Oncology,the First Affiliated Hospital,Chongqing Medical University

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Department of Radiology，The First Affiliated Hospital of Chongqing Medical University

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