Literatures about anti-microbial drugs loaded bone tissue engineering(TE)scaffold were classified according to loaded drug and were extensively reviewed. Processing techniques

feature of drug delivery and anti-infection effect of bone and joint were analyzed. By doing that

we found most of anti-microbial drug loaded bone TE was fabricated successfully currently as an ideal antibiotics delivery system and repair system of bone defects. Kinematics of drug release were detected and anti-microbial effects were demonstrated by in vitro and in vivo experiments. It becomes clear that there have been continued advances

particularly in recent years

however

to the further development of the field

more deep-going researches are necessary prior to clinical application.