Application of mitoxantrone hydrochloride tracer in radical thyroidectomy

LIU Xiao-ming; WU Yi-lei; LIU Xue-jian

doi:10.11659/jjssx.12E022025

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Application of mitoxantrone hydrochloride tracer in radical thyroidectomy

Clinical Research | 更新时间：2024-01-22

- Application of mitoxantrone hydrochloride tracer in radical thyroidectomy
- JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY Vol. 33, Issue 1, Pages: 66-68(2024)
- 作者机构：
  
  山东省立第三医院甲状腺乳腺外科，山东济南 250031
- 作者简介：
- 基金信息：
- DOI：10.11659/jjssx.12E022025
  CLC： R602
- Published：25 January 2024，
  
  Received：05 December 2022，
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刘晓明,武宜雷,刘学键.示踪剂盐酸米托蒽醌在甲状腺癌根治术中的应用[J].局解手术学杂志,2024,33(01):66-68.

LIU Xiao-ming,WU Yi-lei,LIU Xue-jian.Application of mitoxantrone hydrochloride tracer in radical thyroidectomy[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2024,33(01):66-68.
刘晓明,武宜雷,刘学键.示踪剂盐酸米托蒽醌在甲状腺癌根治术中的应用[J].局解手术学杂志,2024,33(01):66-68. DOI： 10.11659/jjssx.12E022025.

LIU Xiao-ming,WU Yi-lei,LIU Xue-jian.Application of mitoxantrone hydrochloride tracer in radical thyroidectomy[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2024,33(01):66-68. DOI： 10.11659/jjssx.12E022025.

摘要

目的

研究示踪剂盐酸米托蒽醌在甲状腺癌根治术中对淋巴结染色率、淋巴结示踪率及甲状旁腺误切率的影响。

方法

选取2022年2月至8月于我院行甲状腺癌根治术的106例患者，随机分为对照组和观察组，每组53例。记录患者淋巴结染色率、示踪持续成功率。比较2组患者淋巴结清除数目、甲状旁腺误切率，及2组患者术前及术后第1天、第3天血钙和甲状旁腺激素（PTH）。

结果

观察组患者淋巴结染色率为90.1%，示踪持续成功率为100%。2组患者淋巴结清除数目，甲状旁腺误切率，术后第1天、第3天血钙和PTH比较差异均有统计学意义（

0.05）。

结论

示踪剂盐酸米托蒽醌具有良好的安全性和淋巴结示踪性，能降低甲状旁腺误切率，值得临床推广应用。

Abstract

Objective

To study the effects of the mitoxantrone hydrochloride tracer on lymph node staining rate，lymph node tracing rate and parathyroid missection rate in radical thyroidectomy.

Methods

A total of 106 patients who received radical thyroidectomy in our hospital from February to August 2022 were selected and randomly divided into the control group and the observation group，with 53 cases in each group. The lymph node staining rate，continuous tracing success rate of patients were recorded，the number of dissected ymph nodes，the parathyroid missection rate of the two groups were compared，and the blood calcium and PTH before surgery and on the first and third day after surgery of the two groups were compared.

Results

The lymph node staining rate in the observation group was 90.1%，and the continuous tracing success rate was 100%. There were statistically significant differences in the number of dissected lymph nodes，parathyroid missection rate，blood calcium and PTH on the first day and third day after surgery between the two groups （

0.05）.

Conclusion

The mitoxantrone hydrochloride tracer has good safety and lymph node traceability，which can reduce the parathyroid missection rate，and is worthy of clinical promotion and application.

关键词

示踪剂盐酸米托蒽醌甲状腺癌淋巴结甲状旁腺

Keywords

tracermitoxantrone hydrochloridethyroid carcinomalymph nodeparathyroid

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