Application of electroencephalogram examination in functional hemispherectomy

CUI Chen-chen; XIAO Qi-hua; CUI Gui-yun; TANG Hai; WANG Xiao-peng; CUI Cheng-cheng; GONG Xiang-yao; ZHOU Man-li

doi:10.11659/jjssx.11E022031

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Application of electroencephalogram examination in functional hemispherectomy

Clinical Research | 更新时间：2023-07-17

- Application of electroencephalogram examination in functional hemispherectomy
- JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY Vol. 32, Issue 7, Pages: 597-599(2023)
- 作者机构：
  
  1.徐州医科大学附属医院功能神经外科，江苏徐州 221000
  2.徐州医科大学附属医院癫痫中心，江苏徐州 221000
- 作者简介：
- 基金信息：
- DOI：10.11659/jjssx.11E022031
  CLC： R61
- Published：25 July 2023，
  
  Received：08 November 2022，
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崔晨晨,肖其华,崔桂云等.脑电图检查在功能性大脑半球切除术中的应用[J].局解手术学杂志,2023,32(07):597-599.

CUI Chen-chen,XIAO Qi-hua,CUI Gui-yun,et al.Application of electroencephalogram examination in functional hemispherectomy[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2023,32(07):597-599.
崔晨晨,肖其华,崔桂云等.脑电图检查在功能性大脑半球切除术中的应用[J].局解手术学杂志,2023,32(07):597-599. DOI： 10.11659/jjssx.11E022031.

CUI Chen-chen,XIAO Qi-hua,CUI Gui-yun,et al.Application of electroencephalogram examination in functional hemispherectomy[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2023,32(07):597-599. DOI： 10.11659/jjssx.11E022031.

摘要

目的

探讨脑电图(EEG)检查（包括术前、术中及术后）在预测功能性大脑半球切除术治疗药物难治性癫痫疗效中的价值。

方法

回顾性分析46例行功能性大脑半球切除术的药物难治性癫痫患者的临床资料，分析术前视频脑电图(V-EEG)、术中皮层及深部EEG、术后V-EEG。分析EEG定位结果与术后疗效的关系，从而探讨EEG的预测价值。

结果

功能性大脑半球切除术后癫痫发作消失37例（80.4%），仍有发作9例（19.6%）。术前V-EEG评估定位对手术疗效无明显影响，术中EEG发现异常放电者术后无发作率为89.7%，明显高于无异常放电者的28.9%（

0.05），术后3个月或6个月对侧有异常放电9例患者，随访2年均出现癫痫发作。

结论

EEG检查与功能性大脑半球切除术疗效存在相关性，结合患者临床资料可有效预测功能性大脑半球切除术的疗效。

Abstract

Objective

To explore the value of electroencephalogram （EEG） examination （including preoperative， intraoperative and postoperative） in predicting the efficacy of functional hemispherectomy in the treatment of drug-resistant epilepsy.

Methods

The clinical data of 46 patients with drug-resistant epilepsy who underwent functional hemispherectomy were retrospectively analyzed， focusing on the preoperative video-electroencephalogram （V-EEG）， intraoperative cortical and deep EEG， and postoperative V-EEG.The relationship between EEG localization results and postoperative curative effect was analyzed to explore the predictive value of EEG.

Results

After functional hemispherectomy， seizures disappeared completely in 37 cases （80.4%）， and still occurred in 9 cases （19.6%）. Preoperative V-EEG localization had no significant effect on the outcome of the operation， the postoperative seizure-free rate of patients with abnormal discharge on EEG during operation was 89.7%，which was significantly higher than 28.9% of patients without abnormal discharge on EEG （

0.05）.There were 9 cases with abnormal contralateral discharge 3 months or 6 months after surgery，seizure occurred in all patients after 2 years of follow-up.

Conclusion

There is a correlation between EEG examination and the efficacy of functional cerebral hemispherectomy，combined with the clinical data of patients， it can effectively predict the efficacy of functional cerebral hemispherectomy.

关键词

功能性大脑半球切除术癫痫脑电图

Keywords

functional hemispherectomyepilepsyelectroencephalogram

references

Bahuleyan B,Robinson S,Nair AR,et al.Anatomic hemispherectomy: historical perspective[J].World Neurosurg,2013,80(3/4):396-398.doi:10.1016/j.wneu.2012.03.020http://dx.doi.org/10.1016/j.wneu.2012.03.020.

Rasmussen T.Hemispherectomy for seizures revisited［J］.Can J Neurol Sci，1983，10（2）：71-78.doi：10.1017/s031716710004466http://dx.doi.org/10.1017/s031716710004466.

Iwasaki M.Hemispherectomy and hemispherotomy in the treatment of drug-resistant epilepsy［J］.No Shinkei Geka，2023，51（1）：126-132.doi： 10.11477/mf.1436204723http://dx.doi.org/10.11477/mf.1436204723.

JrEngel J. International League Against Epilepsy （ILAE）. A proposed diagnostic scheme for people with epileptic seizures and with epilepsy： report of the ILAE Task Force on Classification and Terminology［J］. Epilepsia，2001，42（6）：796-803. doi：10.1046/j.1528-1157. 2001.10401.xhttp://dx.doi.org/10.1046/j.1528-1157.2001.10401.x.

Baumgartner C，Koren JP.Seizure detection using scalp-EEG［J］.Epilepsia，2018，59（Suppl 1）：14-22.doi： 10.1111/epi.14052http://dx.doi.org/10.1111/epi.14052.

Kim JS，Park EK，Shim KW，et al.Hemispherotomy and functional hemispherectomy： indications and outcomes［J］.J Epilepsy Res，2018，8（1）：1-5.doi： 10.14581/jer.18001http://dx.doi.org/10.14581/jer.18001.

Elias GJB，Germann J，Neudorfer C，et al.Impact of mesial temporal lobe resection on brain structure in medically refractory epilepsy［J］.World Neurosurg，2021，152：e652-e665.doi： 10.1016/j.wneu. 2021.06.039http://dx.doi.org/10.1016/j.wneu.2021.06.039.

顾永泉，肖其华，刘毅，等.脑电图检查在海绵状血管瘤所致癫痫定位评估中的应用［J］.癫痫与神经电生理学杂志，2013，22（1）：43-45.doi：10.3969/j.issn.1674-8972.2013.01.013http://dx.doi.org/10.3969/j.issn.1674-8972.2013.01.013.

Ye VC，Shah AH，Sur S，et al.Long-term outcomes after surgery for catastrophic epilepsy in infants： institutional experience and review of the literature［J］．J Neurosurg Pediatr，2020，26（2）：157-164.doi： 10.3171/2020.1.PEDS19537http://dx.doi.org/10.3171/2020.1.PEDS19537.

Young CC，Williams JR，Feroze AH，et al.Pediatric functional hemispherectomy： operative techniques and complication avoidance［J］．Neurosurg Focus，2020，48（4）：E9.doi： 10.3171/2020http://dx.doi.org/10.3171/2020.

马丽峰，刘玉玺.头皮与皮层脑电监测对难治性癫痫不同脑叶致痫灶定位的比较［J］.山西医科大学学报，2011，42（3）：181-184.doi：10.3969/J.ISSN.1007-6611.2011.03.001http://dx.doi.org/10.3969/J.ISSN.1007-6611.2011.03.001.

Alzahrany M，Alnakhli R，Bingaman W，et al.Epileptiform abnormalities in the disconnected hemisphere are common in seizure-free patients after hemispherectomy.Epileptiform abnormalities in the disconnected hemisphere are common in seizure-free patients after hemispherectomy［J］.Epileptic Disord，2022，24（5）：857-866.doi：10.1684/epd.2022.1464http://dx.doi.org/10.1684/epd.2022.1464.

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