Research progress of miR-192 in tumors

MO Ri-gen; YANG Ying-hai; HONG Geerzhula; QI Jirimutu

doi:10.11659/jjssx.10E023112

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Research progress of miR-192 in tumors

Review | 更新时间：2024-12-10

- Research progress of miR-192 in tumors
- JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY Vol. 33, Issue 12, Pages: 1101-1104(2024)
- 作者机构：
  
  锡林郭勒盟蒙医医院胃肠外科，内蒙古锡林浩特026000
- 作者简介：
- 基金信息：
- DOI：10.11659/jjssx.10E023112
  CLC： R73-37
- Published：25 December 2024，
  
  Received：25 October 2023，
- 稿件说明：
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莫日根,杨英海,洪格尔珠拉等.miR-192在肿瘤中的研究进展[J].局解手术学杂志,2024,33(12):1101-1104.

MO Ri-gen,YANG Ying-hai,HONG Geerzhula,et al.Research progress of miR-192 in tumors[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2024,33(12):1101-1104.
莫日根,杨英海,洪格尔珠拉等.miR-192在肿瘤中的研究进展[J].局解手术学杂志,2024,33(12):1101-1104. DOI： 10.11659/jjssx.10E023112.

MO Ri-gen,YANG Ying-hai,HONG Geerzhula,et al.Research progress of miR-192 in tumors[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2024,33(12):1101-1104. DOI： 10.11659/jjssx.10E023112.

摘要

miR-192是一种微小RNA，广泛表达于多种组织中，在细胞分化、凋亡和增殖等生物学过程中扮演着重要角色，并受到转录因子和表观遗传学修饰等多种因素的调控。miR-192的表达在不同组织和疾病中呈现差异性，且在肿瘤中起到抑制肿瘤生长、促进细胞凋亡和转移的作用。miR-192被认为是一种重要的肿瘤基因，在肺癌、乳腺癌、肝癌和结直肠癌中发挥着重要作用。其表达水平的变化可作为潜在的诊断和预后标志物，为这些肿瘤的治疗和预防提供了一定的参考价值。本文探讨miR-192在肿瘤发生、发展及治疗中的作用，揭示其作为肿瘤治疗靶点的潜力。

Abstract

MiR-192 is a kind of microRNA， which is widely expressed in various tissues， and plays an important role in biological processes such as cell differentiation， apoptosis， and proliferation， and is regulated by multiple factors， including transcription factors and epigenetic modifications. The expression of miR-192 varies in different tissues and diseases， and it plays a role in inhibiting tumor growth and promoting cell apoptosis and metastasis in tumors. MiR-192 is considered as a crucial tumor gene，which plays an important role in lung cancer， breast cancer， liver cancer， and colorectal cancer. The expression changes of miR-192 can be used as a potential diagnostic and prognostic markers，which provides certain reference value for the treatment and prevention of these tumors. This article explores the roles of miR-192 in tumor occurrence， progression， and treatment， revealing its potential as a target for tumor treatment.

关键词

miR-192肺癌乳腺癌肝癌结直肠癌

Keywords

miR-192lung cancerbreast cancerliver cancercolorectal cancer

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