LI Hui-min,GAO Qing-ling,JIAO Jian-jun,et al.Comparative study of acellular dermal matrix and pedicle buccal fat pad flap in repairing buccal soft tissue defect[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2024,33(09):825-828.
LI Hui-min,GAO Qing-ling,JIAO Jian-jun,et al.Comparative study of acellular dermal matrix and pedicle buccal fat pad flap in repairing buccal soft tissue defect[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2024,33(09):825-828. DOI: 10.11659/jjssx.10E023062.
Comparative study of acellular dermal matrix and pedicle buccal fat pad flap in repairing buccal soft tissue defect
To compare the efficacies of acellular dermal matrix (ADM) and pedicle buccal fat pad flap (PBFPF) in repairing buccal soft tissue defect.
Methods
2
A total of 84 patients undergoing repair of buccal mucosa defect in our hospital were selected and randomly divided into the ADM group and PBFPF group, with 42 cases in each group.Patients of the ADM group were repaired tby ADM,while patients of the the PBFPF group were repaired by PBFPF.The repair time, oral feeding time,hospital stay were compared between the two groups. The maximum opening degree of patients before surgery, and 1 week, 1 month and 6 months after surgery was measured and compared. The effective rate of repair and the occurrence of complications of patients were recorded. The improvement of oral and maxillofacial function (including swallowing function, language function and masticatory function) after surgery of patients were observed.
Results
2
There was no significant difference in the repair time, oral feeding time, hospital stay, total incidence of complications, postoperative swallowing function or postoperative language function between the two groups (
P
>
0.05).The maximum opening degree had no significant difference between the ADM group and PBFPF group or in the interaction effect between groups and time points (
P
>
0.05), but had significant difference in the comparison of time points (
P
<
0.05).The effective rate of repair for patients with defect area of
>
13~20 cm
2
in the PBFPF group was higher than that in the ADM group (
P
<
0.05).The masticatory function of patients in the PBFPF group was better than that in the ADM group (
P
<
0.05).
Conclusion
2
Both PBFPF and ADM have advantages in the repair of oral mucosal tissue defects, and PBFPF has better repair effect in patients with larger mucosal defect area (
>
13~20 cm
2
).
关键词
颊部软组织缺损脱细胞真皮基质带蒂颊脂垫瓣并发症口腔颌面部功能
Keywords
buccal soft tissue defectacellular dermal matrixpedicle buccal fat pad flapcomplicationsoral and maxillofacial function
Oliveira Neto JQ, Cetira Filho EL, Andrade GS, et al.Technique of the buccal fat pad flap as an alternative for the surgical defect of pleomorphic adenoma[J].J Craniofac Surg,2019,30(3):798-799.doi: 10.1097/SCS.0000000000004890http://dx.doi.org/10.1097/SCS.0000000000004890.
Kearney AM, Yan Y, Bricker JT, et al.Acellular dermal matrix-associated contracture: a clinical and histologic analysis of patients undergoing prosthetic breast reconstruction[J].Plast Reconstr Surg, 2021, 148(5): 968-977.doi: 10.1097/PRS.0000000000008485http://dx.doi.org/10.1097/PRS.0000000000008485.
Goh BKL, Chia HL.The use of acellular dermal matrix in combination with pedicled buccal fat pad in wide cleft palate repair: a case report and literature review[J].Cleft Palate Craniofac J,2019,56(10):1381-1385.doi: 10.1177/1055665619851915http://dx.doi.org/10.1177/1055665619851915.
Wood BC, Mantilla-Rivas E, Goldrich A, et al.Correction of microstomia reconstruction with the use of acellular dermal matrix for buccal reconstruction[J].J Craniofac Surg,2019,30(3):736-738.doi: 10.1097/SCS.0000000000005182http://dx.doi.org/10.1097/SCS.0000000000005182.
Sobhani S, Khaboushan AS, Jafarnezhad-Ansariha F, et al.Off-the-shelf acellular fetal skin scaffold as a novel alternative to buccal mucosa graft: the development and characterization of human tissue-engineered fetal matrix in rabbit model of hypospadiasis[J].Int Urol Nephrol,2022,54(9):2187-2195.doi: 10.1007/s11255-022-03249-7http://dx.doi.org/10.1007/s11255-022-03249-7.
Stefanini M, Rendon A, Zucchelli G.Porcine-derived acellular dermal matrix for buccal soft tissue augmentation at single implant sites: a 1-year follow-up case series[J].Int J Periodontics Restorative Dent, 2020, 40(1):121-128.doi: 10.11607/prd.4477http://dx.doi.org/10.11607/prd.4477.
Wood BC, Mantilla-Rivas E, Goldrich A, et al.Correction of microstomia reconstruction with the use of acellular dermal matrix for buccal reconstruction[J].J Craniofac Surg,2019,30(3):736-738.doi: 10.1097/SCS.0000000000005182http://dx.doi.org/10.1097/SCS.0000000000005182.
Kuo S, Kim HM, Wang Z, et al.Comparison of two decellularized dermal equivalents[J].J Tissue Eng Regen Med,2018,12(4):983-990.doi: 10.1002/term.2530http://dx.doi.org/10.1002/term.2530.
Wang R, Liu W, Guo H, et al.Alveolar ridge preservation with fibroblast growth factor-2 modified acellular dermal matrix membrane and a bovine-derived xenograft: an experimental in vivo study[J].Clin Oral Implants Res,2021,32(7):808-817.doi: 10.1111/clr.13749http://dx.doi.org/10.1111/clr.13749.
Liang NE, Griffin MF, Berry CE, et al.Attenuating chronic fibrosis: decreasing foreign body response with acellular dermal matrix[J].Tissue Eng Part B Rev, 2023,29(6):671-680.doi: 10.1089/ten.TEB.2023.0060http://dx.doi.org/10.1089/ten.TEB.2023.0060.