Radiation dose detection of different sites after <sup>125</sup>I seed implantation in thoracic-abdominal tumors and its significance

XIA Luo-luo; LIAO Xing-ya; LI Xi-ran; HE Chuang; HUANG Xue-quan; QI Xiao-mei

doi:10.11659/jjssx.10E022140

您当前的位置：

首页 >

文章列表页 >

Radiation dose detection of different sites after ¹²⁵I seed implantation in thoracic-abdominal tumors and its significance

Clinical Research | 更新时间：2023-06-13

- Radiation dose detection of different sites after ¹²⁵I seed implantation in thoracic-abdominal tumors and its significance
- JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY Vol. 32, Issue 6, Pages: 519-523(2023)
- 作者机构：
  
  1.陆军军医大学第一附属医院核医学科，重庆 400038
  2.陆军31626部队，广东广州 510800
- 作者简介：
- 基金信息：
- DOI：10.11659/jjssx.10E022140
  CLC： R730.55;R735.9
- Published：25 June 2023，
  
  Received：26 October 2022，
扫描看全文
夏啰啰,廖兴亚,李夕然等.胸腹部肿瘤¹²⁵I粒子植入术后不同位点的辐射剂量检测与意义[J].局解手术学杂志,2023,32(06):519-523.

XIA Luo-luo,LIAO Xing-ya,LI Xi-ran,et al.Radiation dose detection of different sites after ¹²⁵I seed implantation in thoracic-abdominal tumors and its significance[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2023,32(06):519-523.
夏啰啰,廖兴亚,李夕然等.胸腹部肿瘤¹²⁵I粒子植入术后不同位点的辐射剂量检测与意义[J].局解手术学杂志,2023,32(06):519-523. DOI： 10.11659/jjssx.10E022140.

XIA Luo-luo,LIAO Xing-ya,LI Xi-ran,et al.Radiation dose detection of different sites after ¹²⁵I seed implantation in thoracic-abdominal tumors and its significance[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2023,32(06):519-523. DOI： 10.11659/jjssx.10E022140.

摘要

目的

探讨胸腹部肿瘤患者不同数量

125

I粒子植入术后24 h的辐射剂量及安全距离，为医护与陪护人员的防护提供参考。

方法

选取行

125

I粒子植入的胸腹部肿瘤患者100例。根据植入

125

I粒子的数量，采用三分法将患者分为少量组、中量组、大量组。采用γ射线辐射仪分别测量手术侧和对侧0 m、1.0 m、1.5 m、2.0 m距离的辐射剂量并进行重复测量方差分析。

结果

在手术侧与对侧测量中，粒子植入数量分组的组间效应显著（

0.001），测量距离的主效应显著（

0.001），且分组与测量距离存在显著交互效应（

0.001）。手术侧不同距离的辐射剂量也显著大于对侧（

0.001），且与分组存在显著交互效应（

0.001）。2.0 m以上的辐射剂量达到国家标准公众限值（2.50 μSv/h），1.0 m以上的辐射剂量达到国家标准职业限值（25.00 μSv/h）。

结论

125

I粒子植入术后，距离越远防护效果越好，一般人员在离患者2.0 m以上、医护人员在离患者1.0 m以上可无需额外防护，且在患者对侧活动可进一步减少辐射剂量。

Abstract

Objective

To investigate the radiation dose and safe distance of 24 hours after different amounts of

125

I seeds implantation in patients with thoracic-abdominal tumors，so as to provide reference for the protection of medical and accompanying personel.

Methods

A total of 100 patients with thoracic-abdominal tumors treated with

125

I seeds implantation were selected.According to the number of

125

I seeds implanted，the patients were divided into small group，medium group and large group by trichotomy.The radiation dose at the distance of 0 meter，1.0 meter，1.5 meters and 2.0 meters away from the operative side and contralateral side of patients were detected by γ-ray radiometer， and the repeated measurement analysis of variance was performed.

Results

In the detection of the operative side and the contralateral side，there was significant intergroup effect on the number of implanted seeds（

0.001）， a significant main effect on the detection distance （

0.001），and a significant interaction effect between the grouping and the detection distance （

0.001）.The radiation dose at the different distances away from the operative side were also significantly higher than those away from the contralateral side （

0.001），which has a significant interaction effect with the grouping （

0.001）. The radiation dose at the distance above 2.0 meters reached the national standard public limit （2.50 μSv/h），and the radiation dose at the distance above 1 meter reached the national standard occupational limit （25.00 μSv/h）.

Conclusion

After

125

I seeds implantation，the farther the distance，the better the protective effect.The general staff above 2.0 meters away from the patients， medical staff above 1.0 meter away from patients need no additional protection，and the activity on the contralateral side of the patient can further reduce the radiation dose.

关键词

125I粒子肿瘤辐射剂量辐射防护

Keywords

125I seedstumorsradiation doseradiation protection

references

李辉.《中国胸部恶性肿瘤围手术期静脉血栓栓塞症预防与管理指南（2022版）》解读［J］.中国胸心血管外科临床杂志，2022，29（10）：1239-1242.

Xia C，Dong X，Li H，et al.Cancer statistics in China and United States，2022： profiles，trends，and determinants［J］.Chinese Medica Journal，2022，135（5）：584-590.doi：10.1097/CM9.0000000000002108http://dx.doi.org/10.1097/CM9.0000000000002108.

Wang J，Chai S，Wang R，et al.Expert consensus on computed tomography-assisted three-dimensional-printed coplanar template guidance for interstitial permanent radioactive 125I seed implantation therapy.［J］.J Cancer Res Ther，2019，15（7）：1430-1434.doi：10.4103/jcrt.JCRT_434_19http://dx.doi.org/10.4103/jcrt.JCRT_434_19.

Zhang F，Wang J，Guo J，et al.Chinese expert consensus workshop report： Guideline for permanent iodine-125 seeds implantation of

primary and metastatic lung tumors （2020 edition）［J］.J Cancer Res Ther，2020，16（7）：1549-1554.doi：10.4103/jcrt.JCRT_1096_20http://dx.doi.org/10.4103/jcrt.JCRT_1096_20.

Wang G，Zhang F，Yang B，et al.Feasibility and clinical value of CT-guided 125I brachytherapy for bilateral lung recurrences from colorectal carcinoma［J］.Radiology，2016，278（3）：897-905.doi：10.1148/radiol.2015150641http://dx.doi.org/10.1148/radiol.2015150641.

He J，Mai Q，Yang F，et al.Feasibility and clinical value of CT-guided 125I brachytherapy for pain palliation in patients with breast cancer and bone metastases after external beam radiotherapy failure［J］.Front Oncol，2021，11： 627158.doi：10.3389/fonc.2021.627158http://dx.doi.org/10.3389/fonc.2021.627158.

张庆，张方圆，尚芸，等.CT引导下125I放射性粒子植入联合化疗对结直肠癌骨转移患者的应用效果分析［J］.肿瘤综合治疗电子杂志，2022，8（3）：98-102.doi：10.12151/JMCM.2022.03-11http://dx.doi.org/10.12151/JMCM.2022.03-11.

鲁雪妮，宋永春，王妮妮，等.125I粒子植入术后患者周围的辐射监测及其意义［J］.医学信息，2021，34（4）： 171-173.doi：10.3969/j.issn.1006-1959.2021.04.047http://dx.doi.org/10.3969/j.issn.1006-1959.2021.04.047.

纪萍，王姣姣，刘登尧，等.肺部肿瘤患者125I粒子植入术后护士床边交班时不同位置受辐射剂量研究［J］.新疆医科大学学报，2021，

44（7）：857-859.doi：10.3639/j.issn.1009-5551.2021.07.019http://dx.doi.org/10.3639/j.issn.1009-5551.2021.07.019.

姜树坤，王俊杰，闫先瑞，等.放射性125I粒子植入患者术后24 h周围人员及床边剂量检测及年累积剂量预测［J］.中国医学装备，2020，17（3）：14-18.doi：10.3969/J.ISSN.1672-8270.2020. 03.004http://dx.doi.org/10.3969/J.ISSN.1672-8270.2020.03.004.

崔艳玲.放射性I-125粒子植入治疗的辐射防护［J］.中国卫生产业，2017，14（27）：34-35.doi：10.16659/j.cnki.1672-5654.2017. 27.034http://dx.doi.org/10.16659/j.cnki.1672-5654.2017.27.034.

胡永超，杨君，张静.125I放射性粒子植入围术期的安全防护方案应用效果分析［J］.循证护理，2021，7（8）：1101-1104.doi：10.12102/j.issn.2095-866.2021.08.027http://dx.doi.org/10.12102/j.issn.2095-866.2021.08.027.

罗晓丽，李晓燕，张爽.放射性125Ⅰ粒子植入术后密切接触者的辐射安全及防护探究［J］.当代介入医学，2021，1（9）：7-8.doi：10.12208/J.JCIM.2021.09.003http://dx.doi.org/10.12208/J.JCIM.2021.09.003.

蓝绿琴，蒋发烨，陈秀梅，等.肝癌患者植入I125粒子后周围环境辐射剂量率的检测与防护研究［J］.护理学报，2016，23（18）：1-5.doi：10.16460/j.issn1008-9969.2016.18.001http://dx.doi.org/10.16460/j.issn1008-9969.2016.18.001.

陈中乾，何广顺，田丰，等.125Ⅰ粒子植入治疗恶性肿瘤术后散射线防护［J］.现代医用影像学，2021，30（6）：1176-1180.

Cattani F，Vavassori A，Polo A，et al.Radiation exposure after permanent prostate brachytherapy［J］.Radiother Oncol，2006，79（1）：65-69.doi：10.1016/j.radonc.2006.02.010http://dx.doi.org/10.1016/j.radonc.2006.02.010.

贾自玲，徐苗，焦德超，等.新型一体化携125I粒子双链胆道引流管近距离放疗梗阻性黄疸辐射剂量率的监测及防护［J］.介入放射学杂志，2022，31（4）：401-403.doi：10.3969/j.issn.1008-794X.2022.04.017http://dx.doi.org/10.3969/j.issn.1008-794X.2022.04.017.

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

No data

Related Author

No data

Related Institution

No data

⁰

Radiation dose detection of different sites after 125I seed implantation in thoracic-abdominal tumors and its significance

DOI：10.11659/jjssx.10E022140

摘要

Abstract

关键词

Keywords

references

Radiation dose detection of different sites after ¹²⁵I seed implantation in thoracic-abdominal tumors and its significance