Current situation and prospect of surgical treatment of perihilar cholangiocarcinoma
- JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY Vol. 33, Issue 11, Pages: 959-962(2024)
- 作者机构：
1.重庆医科大学第二临床学院，重庆 400010
2.重庆医科大学附属第二医院肝胆外科，重庆 400010
- 作者简介：
- 基金信息：
DOI：10.11659/jjssx.05E023093
CLC： R735.8Published：25 November 2024，
Received：21 May 2023，
- 稿件说明：
移动端阅览
胡议予,汪思宇,朱哲宇等.肝门部胆管癌的外科治疗现状和展望[J].局解手术学杂志,2024,33(11):959-962.
HU Yi-yu,WANG Si-yu,ZHU Zhe-yu,et al.Current situation and prospect of surgical treatment of perihilar cholangiocarcinoma[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2024,33(11):959-962.
胡议予,汪思宇,朱哲宇等.肝门部胆管癌的外科治疗现状和展望[J].局解手术学杂志,2024,33(11):959-962. DOI： 10.11659/jjssx.05E023093.
HU Yi-yu,WANG Si-yu,ZHU Zhe-yu,et al.Current situation and prospect of surgical treatment of perihilar cholangiocarcinoma[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2024,33(11):959-962. DOI： 10.11659/jjssx.05E023093.
摘要
肝门部胆管癌（PHC）是一种常见的胆道恶性肿瘤，外科手术是其最有效的治疗方式，但手术切除后其预后效果不理想。近年来，PHC的外科治疗有了一些新的进展，本文对现有文献进行了回顾，综述了术前减黄、肝增生技术、肝切除术、肝移植术和微创手术等治疗方式在PHC中的治疗现状，并对其未来的研究方向进行了展望。
Abstract
Perihilar cholangiocarcinoma （PHC） is a common malignancy of biliary tract， for which surgery is the most effective treatment.However，its prognosis is not satisfactory even after surgical resection.In recent years，there have been some new advances in the surgical treatment of PHC.In this paper，we reviewed the existing literatures，demonstrated the current situation of preoperative biliary drainage，liver hyperplasia，hepatic resection，liver transplantation and minimally invasive surgery in the treatment of PHC，and prospected the future research direction.
关键词
肝门部胆管癌术前减黄肝切除术肝移植术现状展望
Keywords
perihilar cholangiocarcinomapreoperative biliary drainagehepatic resectionliver transplantationcurrent situationprospect
references
刘学青，周新博，胡子轩，等. 腹腔镜肝门部胆管癌根治术的临床疗效［J］.中华消化外科杂志，2023，22（7）：884-890.doi：10.3760/cma.j.cn115610-20230519-00222http://dx.doi.org/10.3760/cma.j.cn115610-20230519-00222.
王宏光，罗漫.肝门部胆管癌的术前评估和术中导航研究进展［J］.中华消化外科杂志，2024，23（7）：906-911.doi：10.3760/cma.j.cn115610-20240612-00291http://dx.doi.org/10.3760/cma.j.cn115610-20240612-00291.
Pavlidis ET，Pavlidis TE.Pathophysiological consequences of obstructive jaundice and perioperative management［J］.Hepatobiliary Pancreat Dis Int，2018，17（1）：17-21.doi：10.1016/j.hbpd.2018.01.008http://dx.doi.org/10.1016/j.hbpd.2018.01.008.
Whipple AO，Parsons WB，Mullins CR.Treatment of carcinoma of the ampulla of vater ［J］.Ann Surg，1935，102（4）：763-779.doi：10.1097/00000658-193510000-00023http://dx.doi.org/10.1097/00000658-193510000-00023.
Xiong JJ，Nunes QM，Huang W，et al.Preoperative biliary drainage in patients with hilar cholangiocarcinoma undergoing major hepatectomy［J］.World J Gastroenterol，2013，19（46）：8731-8739.doi：10.3748/wjg.v19.i46.8731http://dx.doi.org/10.3748/wjg.v19.i46.8731.
Ramanathan R，Borrebach J，Tohme S，et al.Preoperative biliary drainage is associated with increased complications after liver resection for proximal cholangiocarcinoma［J］.J Gastrointest Surg，2018，22（11）：1950-1957.doi： 10.1007/s11605-018-3861-3http://dx.doi.org/10.1007/s11605-018-3861-3.
Farges O，Regimbeau JM，Fuks D，et al.Multicentre European study of preoperative biliary drainage for hilar cholangiocarcinoma［J］.Br J Surg，2013，100（2）：274-283.doi：10.1002/bjs.8950http://dx.doi.org/10.1002/bjs.8950.
Mehrabi A，Khajeh E，Ghamarnejad O，et al.Meta-analysis of the efficacy of preoperative biliary drainage in patients undergoing liver resection for perihilar cholangiocarcinoma［J］.Eur J Radiol，2020，125：108897.doi：10.1016/j.ejrad.2020.108897http://dx.doi.org/10.1016/j.ejrad.2020.108897.
Paik WH，Loganathan N，Hwang JH.Preoperative biliary drainage in hilar cholangiocarcinoma：when and how？［J］.World J Gastrointest Endosc，2014，6（3）：68-73.doi：10.4253/wjge.v6.i3.68http://dx.doi.org/10.4253/wjge.v6.i3.68.
唐鹏，王槐志.术前胆道引流在远端恶性胆道梗阻治疗中的研究进展［J］.临床医学进展，2023，13：7312-7319.doi：10.12677/ACM.2023.1351022http://dx.doi.org/10.12677/ACM.2023.1351022.
银蒋，吴天柱，龚建平.肝门部胆管癌术前引流必要性及引流方式的探讨［J］.临床医学进展，2021，11（4）：1952-1958.doi：10.12677/ACM.2021.114281http://dx.doi.org/10.12677/ACM.2021.114281.
Mocan T，Horhat A，Mois E，et al.Endoscopic or percutaneous biliary drainage in hilar cholangiocarcinoma：when and how？［J］.World J Gastrointest Oncol，2021，13（12）：2050-2063.doi：10.4251/wjgo.v13.i12.2050http://dx.doi.org/10.4251/wjgo.v13.i12.2050.
Yamao K，Kitano M，Takenaka M，et al.Outcomes of endoscopic biliary drainage in pancreatic cancer patients with an indwelling gastroduodenal stent： a multicenter cohort study in West Japan［J］. Gastrointest Endosc，2018，88（1）：66-75.e62.doi：10.1016/j.gie.2018.01.021http://dx.doi.org/10.1016/j.gie.2018.01.021.
中国抗癌协会. 肝门部胆管癌规范化诊治专家共识（2015）［J］.中华肝胆外科杂志，2015，21（8）：505-511. doi：10.3760/cma.j.issn.1007-8118.2015.08.001http://dx.doi.org/10.3760/cma.j.issn.1007-8118.2015.08.001.
Olthof PB，Aldrighetti L，Alikhanov R，et al.Portal vein embolization is associated with reduced liver failure and mortality in high-risk resections for perihilar cholangiocarcinoma［J］.Ann Surg Oncol，2020，27（7）：2311-2318.doi：10.1245/s10434-020-08258-3http://dx.doi.org/10.1245/s10434-020-08258-3.
Xiang F，Hu ZM.Chance and challenge of associating liver partition and portal vein ligation for staged hepatectomy［J］.Hepatobiliary Pancreat Dis Int，2019，18（3）：214-222.doi：10.1016/j.hbpd.2019.04.006http://dx.doi.org/10.1016/j.hbpd.2019.04.006.
Bismuth H， Corlette MB.Intrahepatic cholangioenteric anastomosis in carcinoma of the hilus of the liver［J］.Surg Gynecol Obstet，1975，140（2）：170-178.
Chen RX，Li CX，Luo CH，et al.Surgical strategies for the treatment of bismuth type Ⅰ and Ⅱ hilar cholangiocarcinoma：bile duct resection with or without hepatectomy？［J］.Ann Surg Oncol，2020，27（9）：3374-3382.doi：10.1245/s10434-020-08453-2http://dx.doi.org/10.1245/s10434-020-08453-2.
Ku D，Tang R，Pang T，et al.Survival outcomes of hepatic resections in Bismuth‐Corlette type Ⅳ cholangiocarcinoma［J］.ANZ J Surg，2019，90（9）：1604-1614.doi：10.1111/ans.15531http://dx.doi.org/10.1111/ans.15531.
Zhang XF，Zhang N，Tsilimigras DI，et al.Surgical strategies for Bismuth type Ⅰ and Ⅱ hilar cholangiocarcinoma：impact on long-term outcomes［J］.J Gastrointest Surg，2021，25（12）：3084-3091. doi：10.1007/s11605-021-05049-3http://dx.doi.org/10.1007/s11605-021-05049-3.
Hu YF，Hu HJ，Lv TR，et al.Should more aggressive surgical resection be considered in the treatment for Bismuth types Ⅰ and Ⅱ hilar cholangiocarcinoma？A meta-analysis［J］.Asian J Surg，2023，46（10）：4115-4123.doi：10.1016/j.asjsur.2022.12.043http://dx.doi.org/10.1016/j.asjsur.2022.12.043.
Bhutiani N，Scoggins CR，McMasters KM，et al.The impact of caudate lobe resection on margin status and outcomes in patients with hilar cholangiocarcinoma：a multi-institutional analysis from the US Extrahepatic Biliary Malignancy Consortium［J］.Surgery，2018，163（4）：726-731.doi：10.1016/j.surg.2017.10.028http://dx.doi.org/10.1016/j.surg.2017.10.028.
Birgin E，Rasbach E，Reissfelder C，et al.A systematic review and meta-analysis of caudate lobectomy for treatment of hilar cholangiocarcinoma［J］.Eur J Surg Oncol，2020，46（5）：747-753.doi： 10.1016/j.ejso.2020.01.023http://dx.doi.org/10.1016/j.ejso.2020.01.023.
Gilbert RWD，Lenet T，Cleary SP，et al.Does caudate resection improve outcomes of patients undergoing curative resection for perihilar cholangiocarcinoma？A systematic review and meta-analysis［J］.Ann Surg Oncol，2022，29（11）：6759-6771.doi：10.1245/s10434-022-11990-7http://dx.doi.org/10.1245/s10434-022-11990-7.
Liu ZP，Chen WY，Zhang YQ，et al.Postoperative morbidity adversely impacts oncological prognosis after curative resection for hilar cholangiocarcinoma［J］. World J Gastroenterol，2022，28（9）：948-960.doi： 10.3748/wjg.v28.i9.948http://dx.doi.org/10.3748/wjg.v28.i9.948.
Feng JW，Yang XH，Wu BQ，et al.Progress in diagnosis and surgical treatment of perihilar cholangiocarcinoma［J］.Gastroenterol Hepatol，2019，42（4）：271-279.doi：10.1016/j.gastrohep.2018.11.003http://dx.doi.org/10.1016/j.gastrohep.2018.11.003.
Meyer CG， Penn I， James L.Liver transplantation for cholangiocarcinoma：results in 207 patients［J］.Transplantation，2000，69（8）：1633-1637.doi：10.1097/00007890-200004270-00019http://dx.doi.org/10.1097/00007890-200004270-00019.
Moris D，Kostakis ID，Machairas N，et al.Comparison between liver transplantation and resection for hilar cholangio carcinoma：a systematic review and meta-analysis［J］.PLoS One，2019，14（7）：e0220527.doi：10.1371/journal.pone.0220527http://dx.doi.org/10.1371/journal.pone.0220527.
Machairas N， Kostakis ID， Tsilimigras DI，et al.Liver transplantation for hilar cholangiocarcinoma：a systematic review［J］.Transplant Rev （Orlando），2020，34（1）：100516.doi：10.1016/j.trre.2019.100516http://dx.doi.org/10.1016/j.trre.2019.100516.
Ito T，Butler JR，Noguchi D，et al.A 3‐decade，single‐center experience of liver transplantation for cholangiocarcinoma：impact of era，tumor size，location，and neoadjuvant therapy［J］.Liver Transplantation，2021， 28（3）：386-396.doi： 10.1002/lt.26285http://dx.doi.org/10.1002/lt.26285.
Hoogwater FJH，Kuipers H，de Meijer VE，et al.Role of neoadjuvant chemoradiotherapy in liver transplantation for unresectable perihilar cholangiocarcinoma：multicentre，retrospective cohort study［J］.BJS Open，2023，7（2）：zrad025.doi：10.1093/bjsopen/zrad025http://dx.doi.org/10.1093/bjsopen/zrad025.
Panayotova G，Lunsford KE，Latt NL，et al.Expanding indications for liver transplantation in the era of liver transplant oncology［J］. World J Gastrointest Surg，2021，13（5）：392-405.doi： 10.4240/wjgs.v13.i5.392http://dx.doi.org/10.4240/wjgs.v13.i5.392.
Kawano F，Yoshioka R，Ichida H，et al.Essential updates 2021/2022：update in surgical strategy for perihilar cholangiocarcinoma［J］.Ann Gastroenterol Surg，2023，7（6）：848-855.doi：10.1002/ags3.12734http://dx.doi.org/10.1002/ags3.12734.
Verna EC，Patel YA，Aggarwal A，et al.Liver transplantation for hepatocellular carcinoma：management after the transplant［J］.Am J Transplant，2020，20（2）：333-347.doi：10.1111/ajt.15697http://dx.doi.org/10.1111/ajt.15697.
Twohig P，Peeraphatdit TB，Mukherjee S.Current status of liver transplantation for cholangiocarcinoma［J］.World J Gastrointest Surg，2022，14（1）：1-11.doi：10.4240/wjgs.v14.i1.1http://dx.doi.org/10.4240/wjgs.v14.i1.1.
Safarpour AR，Askari H，Ejtehadi F，et al.Cholangiocarcinoma and liver transplantation：what we know so far？［J］.World J Gastrointest Pathophysiol，2021，12（5）：84-105. doi：10.4291/wjgp.v12.i5.84http://dx.doi.org/10.4291/wjgp.v12.i5.84.
Xiong F，Peng F，Li X，et al.Preliminary comparison of total laparoscopic and open radical resection for hepatic hilar cholangiocarcinoma a single-center cohort study［J］.Asian J Surg，2023，46（2）：856-862.doi：10.1016/j.asjsur.2022.07.158http://dx.doi.org/10.1016/j.asjsur.2022.07.158.
Franken LC，van der Poel MJ，Latenstein AEJ，et al.Minimally invasive surgery for perihilar cholangiocarcinoma：a systematic review［J］.J Robot Surg，2019，13（6）：717-727.doi： 10.1007/s11701-019-00964-9http://dx.doi.org/10.1007/s11701-019-00964-9.
Li JD，Xiong YF，Gang Y，et al.Minimally invasive surgery for hilar cholangiocarcinoma：a multicenter retrospective analysis of 158 patients［J］.Surg Endosc，2021，35（12）：6612-6622.doi： 10.1007/s00464-020-08161-8http://dx.doi.org/10.1007/s00464-020-08161-8.
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