Effects of microsurgical varicocelectomy on testicular function and sexual function in patients with varicocele

TIAN Cheng; CAO Xu; YANG Yue-yue; GAO Jie; ZENG Yu-xiao; YAO Jian-zhong

doi:10.11659/jjssx.03E023134

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Effects of microsurgical varicocelectomy on testicular function and sexual function in patients with varicocele

Clinical Research | 更新时间：2024-04-01

- Effects of microsurgical varicocelectomy on testicular function and sexual function in patients with varicocele
- JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY Vol. 33, Issue 3, Pages: 213-216(2024)
- 作者机构：
  
  中国人民解放军联勤保障部队第九二〇医院泌尿外科，云南昆明 650032
- 作者简介：
- 基金信息：
- DOI：10.11659/jjssx.03E023134
  CLC： R697+.24
- Published：25 March 2024，
  
  Received：21 March 2023，
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田成,曹溆,杨月月等.显微镜下精索静脉结扎术对精索静脉曲张患者睾丸功能及性功能的影响[J].局解手术学杂志,2024,33(03):213-216.

TIAN Cheng,CAO Xu,YANG Yue-yue,et al.Effects of microsurgical varicocelectomy on testicular function and sexual function in patients with varicocele[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2024,33(03):213-216.
田成,曹溆,杨月月等.显微镜下精索静脉结扎术对精索静脉曲张患者睾丸功能及性功能的影响[J].局解手术学杂志,2024,33(03):213-216. DOI： 10.11659/jjssx.03E023134.

TIAN Cheng,CAO Xu,YANG Yue-yue,et al.Effects of microsurgical varicocelectomy on testicular function and sexual function in patients with varicocele[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2024,33(03):213-216. DOI： 10.11659/jjssx.03E023134.

摘要

目的

探讨精索静脉曲张患者行显微镜下精索静脉结扎术对睾丸功能及性功能的影响。

方法

回顾性分析我院收治的90例精索静脉曲张患者的临床资料，根据手术方法不同将患者分为腹腔镜组（采用腹腔镜下精索静脉结扎术治疗）和显微镜组（采用显微镜下精索静脉结扎术治疗），每组45例。比较2组患者术前及术后6个月精子密度、正常形态精子比例、（a+b）级精子率、向前运动精子率、国际勃起功能指数-5（IIEF-5）评分及睾酮、卵泡刺激素、黄体生成素、雄激素水平等睾丸功能和性功能相关指标。统计2组患者术后6个月并发症发生及复发情况。

结果

与术前比较，2组患者术后6个月精子密度、向前运动精子率、（a+b）级精子率、正常形态精子比例、IIEF-5评分、睾酮水平、雄激素水平均明显升高（

0.05），黄体生成素、卵泡刺激素水平均降低（

0.05）。与腹腔镜组比较，显微镜组患者术后6个月卵泡刺激素水平、黄体生成素水平及并发症发生率降低（

0.05），睾酮水平、雄激素水平、IIEF-5评分升高（

0.05）。2组患者复发率比较，差异无统计学意义（

0.05）。

结论

显微镜下精索静脉结扎术治疗精索静脉曲张可改善患者睾丸功能及性功能，且并发症发生率低。

Abstract

Objective

To investigate the effects of microsurgical varicocelectomy on testicular function and sexual function in patients with varicocele.

Methods

The clinical data of 90 patients with varicocele admitted to our hospital were retrospectively analyzed， and the patients were divided into the laparoscopic group （received laparoscopic varicocelectomy） and the microscopic group （received microsurgical varicocelectomy） according to different surgical methods， with 45 cases in each group. The testicular function and sexual function related indexes including sperm density， normal sperm ratio， rate of sperm motility （grades a+b）， forward motility sperm rate， international index of erectile function-5 （IIEF-5） score， and the levels of testosterone， follicle-stimulating hormone， luteinizing hormone， and androgen levels before and 6 months after surgery in the two groups were compared. The incidence of complications and recurrence 6 months after surgery in the two groups were counted.

Results

Compared with those before surgery， the sperm density， forward motility sperm rate， rate of sperm motility （grades a+b）， normal sperm ratio， IIEF-5 score， testosterone level， and androgen level 6 months after surgery of patients in the two groups were significantly increased （

0.05）， and the levels of luteinizing hormone and follicle-stimulating hormone were decreased （

0.05）. Compared with the laparoscopic group， the levels of follicle-stimulating hormone and luteinizing hormone， and incidence of complications 6 months after surgery of patients in the microscopic group were decreased （

0.05）， and the levels of testosterone and androgens， and IIEF-5 score 6 months after surgery were increased （

0.05）. There was no significant difference in the recurrence rate between the two groups （

0.05）.

Conclusion

Microsurgical varicocelectomy can improve the testicular function and sexual function of patients with varicocele， with a low incidence of complications.

关键词

显微镜腹腔镜精索静脉结扎术精索静脉曲张睾丸功能性功能

Keywords

microscopelaparoscopevaricocelectomyvaricoceletesticular functionsexual function

references

Lobe C，Vallette M，Arbelaiz A，et al.Zinc finger E-box binding homeobox 1 promotes cholangiocarcinoma progression through tumor dedifferentiation and tumor-stroma paracrine signaling［J］.Hepatology，2021，74（6）：3194-3212.doi：10.1002/hep.32069http://dx.doi.org/10.1002/hep.32069.

Oster J.Varicocele in children and adolescents.An investigation of the incidence among Danish school children［J］.Scand J Urol Nephrol，1971，5（1）：27-32.doi：10.3109/00365597109133569http://dx.doi.org/10.3109/00365597109133569.

张思州，潘俊呈，温鹏，等.腹腔镜下精索静脉高位结扎术联合迈之灵治疗精索静脉曲张的疗效分析［J］.检验医学与临床，2021，18（22）：3316-3318.doi：10.3969/j.issn.1672-9455.2021.22.028http://dx.doi.org/10.3969/j.issn.1672-9455.2021.22.028.

周杰，柳乐毅，朱俊超.睾丸内精索静脉曲张的诊疗现状［J］.国际泌尿系统杂志，2022，42（6）：1144-1146.doi：10.3760/cma.j.cn431460-20210205-00306http://dx.doi.org/10.3760/cma.j.cn431460-20210205-00306.

张立元，张小康，剡锐，等.双侧精索静脉曲张手术治疗方式选择的探讨［J］.中国男科学杂志，2021，35（2）：50-53.doi：10.3969/j.issn.1008-0848.2021.02.011http://dx.doi.org/10.3969/j.issn.1008-0848.2021.02.011.

盛一帆，李子祥，夏斌，等.不同手术方式治疗单侧原发性精索静脉曲张的疗效［J］.局解手术学杂志，2021，30（5）：429-433.doi：10.11659/jjssx.10E020062http://dx.doi.org/10.11659/jjssx.10E020062.

朱磊磊，黄兴.Wink切口下显微镜精索静脉结扎术与腹腔镜下精索静脉高位结扎术疗效对比［J］.中国医学创新，2023，20（14）：46-49.doi：10.3969/j.issn.1674-4985.2023.14.011http://dx.doi.org/10.3969/j.issn.1674-4985.2023.14.011.

中华医学会男科学分会，精索静脉曲张诊断与治疗指南编写组，孙祥宙.精索静脉曲张诊断与治疗指南［J］.中华男科学杂志，2022，28（8）：756-767.doi：10.13263/j.cnki.nja.2022.08.010http://dx.doi.org/10.13263/j.cnki.nja.2022.08.010.

张唯力，徐光勇，刘川.勃起功能国际指数5与夜间阴茎勃起实验在诊断勃起功能障碍中的应用［J］.中华泌尿外科杂志，2004，25（8）：67.doi：10.3760/j：issn：1000-6702.2004.08.038http://dx.doi.org/10.3760/j：issn：1000-6702.2004.08.038.

仲崇副，刘丰瑞，史卓卓，等.脉络舒通丸治疗精索静脉曲张的组方机制［J］.世界中医药，2021，16（18）：2794-2797.doi：10.3969/j.issn.1673-7202.2021.18.025http://dx.doi.org/10.3969/j.issn.1673-7202.2021.18.025.

李海博，潘锋，张峰磊，等.显微外科精索静脉低位结扎术对精索静脉曲张患者生育功能及性功能的影响［J］.海南医学，2023，34（24）：3618-3621.doi：10.3969/j.issn.1003-6350.2023.24. 026http://dx.doi.org/10.3969/j.issn.1003-6350.2023.24.026.

余莉，梅建勇，李甜，等.精索静脉曲张腹腔镜或显微镜下精索内静脉高位结扎术对患者精液质量影响［J］.中国计划生育学杂志，2022，30（8）：1745-1753.doi：10.3969/j.issn.1004-8189. 2022.08.009http://dx.doi.org/10.3969/j.issn.1004-8189.2022.08.009.

马际尧，袁金成，邱建宏，等.腹腔镜下精索静脉高位结扎术治疗复发性精索静脉曲张的疗效分析［J］.中国男科学杂志，2021，35（5）：42-46.doi：10.3969/j.issn.1008-0848.2021.05.008http://dx.doi.org/10.3969/j.issn.1008-0848.2021.05.008.

王钰，李清华，张超，等.显微镜下精索静脉结扎术治疗青春期精索静脉曲张的疗效［J］.安徽医学，2021，42（2）：190-192.doi：10.3969/j.issn.1000-0399.2021.02.018http://dx.doi.org/10.3969/j.issn.1000-0399.2021.02.018.

Vyas HG，Bhandari V，Kumar A，et al.A prospective randomized comparative trial between open subinguinal and loupe assisted subinguinal varicocelectome：a single center experience［J］.Urol Ann，2017，9（1）：13-17.doi：10.4103/0974-7796.198899http://dx.doi.org/10.4103/0974-7796.198899.

刘龙强，白如玉，汪峰，等.显微镜精索静脉结扎术对精索静脉曲张患者性功能影响的临床研究［J］.中国性科学，2018，27（2）：9-12.doi：10.3969/j.issn.1009-4393.2019.11.010http://dx.doi.org/10.3969/j.issn.1009-4393.2019.11.010.

高华，李世江.腹腔镜与显微镜下精索静脉结扎术对精索静脉曲张性不育患者生殖激素及精液质量影响的对比研究［J］.中国社区医师，2017，33（35）：58-61.doi：10.3969/j.issn.1007-614x.2017.35.32http://dx.doi.org/10.3969/j.issn.1007-614x.2017.35.32.

彭靖，方冬，张志超，等.精索静脉曲张或无精子症男性的睾酮水平［J］.北京大学学报（医学版），2022，54（2）：294-298.doi：10.19723/j.issn.1671-167X.2022.02.016http://dx.doi.org/10.19723/j.issn.1671-167X.2022.02.016.

杨乐，朱平宇，李云祥.显微镜下精索静脉结扎术对精索静脉曲张患者手术时间、睾酮水平及精子质量的影响［J］.临床和实验医学杂志，2021，20（5）：515-518.doi：10.3969/j.issn.1671-4695.2021.05.018http://dx.doi.org/10.3969/j.issn.1671-4695.2021.05.018.

Cayan S，Shavakhabov S，Kadioğlu A.Treatment of palpable varicocele in infertile men：a meta-analysis to define the best technique［J］.J Androl，2009，30（1）：33-40.doi：10.2164/jandrol.108.005967http://dx.doi.org/10.2164/jandrol.108.005967.

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