Curative effect and prognosis of Zheng's 4C suspension transumbilical laparoendoscopic single-site surgery for cervical cancer

HE Qiu-min; ZHANG Chong-yuan; ZHANG Si-si; HU Yao

doi:10.11659/jjssx.02E023069

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Curative effect and prognosis of Zheng's 4C suspension transumbilical laparoendoscopic single-site surgery for cervical cancer

Clinical Research | 更新时间：2024-02-02

- Curative effect and prognosis of Zheng's 4C suspension transumbilical laparoendoscopic single-site surgery for cervical cancer
- JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY Vol. 33, Issue 2, Pages: 162-165(2024)
- 作者机构：
  
  荆州市中心医院/长江大学附属荆州医院妇产科，湖北荆州 434000
- 作者简介：
- 基金信息：
- DOI：10.11659/jjssx.02E023069
  CLC： R711.74
- Published：25 February 2024，
  
  Received：14 February 2023，
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何秋敏,张崇媛,张思思等.郑氏4C悬吊法经脐单孔腹腔镜手术治疗宫颈癌的疗效及预后分析[J].局解手术学杂志,2024,33(02):162-165.

HE Qiu-min,ZHANG Chong-yuan,ZHANG Si-si,et al.Curative effect and prognosis of Zheng's 4C suspension transumbilical laparoendoscopic single-site surgery for cervical cancer[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2024,33(02):162-165.
何秋敏,张崇媛,张思思等.郑氏4C悬吊法经脐单孔腹腔镜手术治疗宫颈癌的疗效及预后分析[J].局解手术学杂志,2024,33(02):162-165. DOI： 10.11659/jjssx.02E023069.

HE Qiu-min,ZHANG Chong-yuan,ZHANG Si-si,et al.Curative effect and prognosis of Zheng's 4C suspension transumbilical laparoendoscopic single-site surgery for cervical cancer[J].JOURNAL OF REGIONAL ANATOMY AND OPERATIVE SURGERY,2024,33(02):162-165. DOI： 10.11659/jjssx.02E023069.

摘要

目的

探讨郑氏4C悬吊法经脐单孔腹腔镜手术（TU-LSSS）治疗宫颈癌的疗效，并分析其预后。

方法

选取我院收治的宫颈癌患者92例，并随机分为对照组（传统腹腔镜术）和观察组（郑氏4C悬吊法TU-LSSS），每组46例。比较2组患者围术期相关指标。随访3年，记录患者无进展生存期（PFS）和总生存期（OS），并分析预后的影响因素。

结果

与对照组比较，观察组患者手术时间更长（

0.05），术中出血量更少（

0.05），术后肠鸣音恢复时间、住院时间更短（

0.05），术后3年PFS率、3年OS率更高（

0.05）。随访3年，疾病进展或死亡共11例。经单因素分析，预后良好组与预后不良组患者肿瘤直径、临床分期、淋巴结转移、脉管浸润、治疗方法比较，差异有统计学意义（

0.05）；二元

Logistic

回归分析显示，肿瘤直径（≥4 cm）、临床分期（≥ⅠB2期）、淋巴结转移、脉管浸润是宫颈癌预后的危险因素（

0.05），郑氏4C悬吊法TU-LSSS是保护因素（

0.05）。

结论

郑氏4C悬吊法TU-LSSS治疗宫颈癌可有效促进患者恢复，提高3年PFS率和OS率。预后与多种因素有关，需根据不同危险因素给予针对性处理。

Abstract

Objective

To investigate the effect of Zheng's 4C suspension transumbilical laparoendoscopic single-site surgery （TU-LSSS） in the treatment of cervical cancer，and analyze its prognosis.

Methods

A total of 92 patients with cervical cancer admitted to our hospital were selected and randomly divided into the control group （traditional laparoscopic surgery） and the observation group （Zheng's 4C suspension TU-LSSS），with 46 cases in each group. The perioperative related indicators of patients between the two groups were compared. The patients were followed up for 3 years，the progression-free survival （PFS） and overall survival （OS） were recorded，and the influencing factors of prognosis were analyzed.

Results

Compared with the control group，patients in the observation group had longer surgical time （

0.05），less intraoperative bleeding （

0.05），shorter recovery time for postoperative bowel sounds and hospital stay （

0.05），higher postoperative 3-year PFS rate and 3-year OS rate （

0.05）. During 3-year follow-up，there were 11 cases of disease progression or death. The univariate analysis results showed that there were statistically significant differences in tumor diameter，clinical stage，lymph node metastasis，vascular infiltration，and treatment methods of patients between the good prognosis group and the poor prognosis group （

0.05）. The binary

Logistic

regression results showed that tumor diameter （≥4 cm），clinical stage （≥stage ⅠB2），lymph node metastasis，and vascular infiltration were the risk factors for the prognosis of patietns with cervical cancer （

0.05），while Zheng's 4C suspension TU-LSSS was the protective factors （

0.05）.

Conclusion

Zheng's 4C suspension TU-LSSS can effectively promote the recovery of patients with cervical cancer，and improve 3-year PFS rate and 3-year OS rate.The prognosis is related to many factors，and targeted treatment should be performed according to different risk factors.

关键词

郑氏4C悬吊法经脐单孔腹腔镜手术宫颈癌疗效预后

Keywords

Zheng's 4C suspension methodtransumbilical laparoendoscopic single-site surgerycervical cancerefficacyprognosis

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