Integrated bulk and single-cell transcriptome data identify clinically relevant cell populations in clear cell renal cell carcinoma

Pingbao Zhang; Pu Zhang; Jun Gao; Xiaosong Li; Chengcheng Wei; Weihui Liu; QingLiu He; Yuan Zhang

doi:10.1016/j.gendis.2023.03.007

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Integrated bulk and single-cell transcriptome data identify clinically relevant cell populations in clear cell renal cell carcinoma

Short communication | 更新时间：2024-02-04

- Integrated bulk and single-cell transcriptome data identify clinically relevant cell populations in clear cell renal cell carcinoma
- Genes & Diseases Vol. 1, Issue 1, Pages: 42-45(2024)
- 作者机构：
  
  1. Department of Urology, Zhongshan Hospital, Fudan University,Shanghai,China,200032
  2. Department of Urology Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology,Hubei,Wuhan,China,430022
  3. Department of Liver Surgery and Transplantation, Liver Cancer Institute, Zhongshan Hospital, Fudan University,Shanghai,China,200032
  4. Clinical Molecular Medicine Testing Center, The First Affiliated Hospital of Chongqing Medical University,Chongqing,China,400016
  5. Department of Urology, The Second Affiliated Hospital of Fujian Medical University,Fujian,Quanzhou,China,362000
  6. Department of Nephrology, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China,Sichuan,Chengdu,China,610072
- 作者简介：
- 基金信息：
- DOI：10.1016/j.gendis.2023.03.007
  CLC：
- Published：2024，
  
  Published Online：1 January 2024，
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Pingbao Zhang, Pu Zhang, Jun Gao, et al. Integrated bulk and single-cell transcriptome data identify clinically relevant cell populations in clear cell renal cell carcinoma. [J]. Genes & Diseases 1(1):42-45(2024)
DOI：

Pingbao Zhang, Pu Zhang, Jun Gao, et al. Integrated bulk and single-cell transcriptome data identify clinically relevant cell populations in clear cell renal cell carcinoma. [J]. Genes & Diseases 1(1):42-45(2024) DOI： 10.1016/j.gendis.2023.03.007.

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1 P. Makhov, S. Joshi, P. Ghatalia, et al.Resistance to systemic therapies in clear cell renal cell carcinoma: mechanisms and management strategies Mol Cancer Therapeut, 17 (7) (2018), pp. 1355-1364

2 M.D. Young, T.J. Mitchell, F.A. Vieira Braga, et al.Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors Science, 361 (6402) (2018), pp. 594-599

3 Y. Zhang, S.P. Narayanan, R. Mannan, et al.Single-cell analyses of renal cell cancers reveal insights into tumor microenvironment, cell of origin, and therapy response Proc Natl Acad Sci U S A, 118 (24) (2021), Article e2103240118

4 C.G.A.R. NetworkComprehensive molecular characterization of clear cell renal cell carcinoma Nature, 499 (7456) (2013), pp. 43-49

5 M.L. Ascierto, T.L. McMiller, A.E. Berger, et al.The intratumoral balance between metabolic and immunologic gene expression is associated with anti-PD-1 response in patients with renal cell carcinoma Cancer Immunol Res, 4 (9) (2016), pp. 726-733

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