Transcriptomic analysis identifies the S100 calcium-binding protein β subunit (S100B) and intercellular adhesion molecule-1 (ICAM-1) as potential diagnostic biomarkers for acute cerebral infarction

Dan Cheng; Yushuo Wang; Jingna Li; Yulan Yao; Simiao Zhang; Yunliang Wang

doi:10.1016/j.gendis.2023.03.006

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Transcriptomic analysis identifies the S100 calcium-binding protein β subunit (S100B) and intercellular adhesion molecule-1 (ICAM-1) as potential diagnostic biomarkers for acute cerebral infarction

Short communication | 更新时间：2024-02-04

- Transcriptomic analysis identifies the S100 calcium-binding protein β subunit (S100B) and intercellular adhesion molecule-1 (ICAM-1) as potential diagnostic biomarkers for acute cerebral infarction
- Genes & Diseases Vol. 1, Issue 1, Pages: 46-48(2024)
- 作者机构：
  
  1. Department of Neurology, Second Affiliated Hospital of Zhengzhou University,Henan,Zhengzhou,China,450014
  2. School of Medicine, Medical Sciences and Nutrition University of Aberdeen,Aberdeen,UK,AB25 2ZD
  3. Department of Neurology, The 960th Hospital of PLA,Shandong,Zibo,China,255300
- 作者简介：
- 基金信息：
- DOI：10.1016/j.gendis.2023.03.006
  CLC：
- Published：2024，
  
  Published Online：1 January 2024，
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Dan Cheng, Yushuo Wang, Jingna Li, et al. Transcriptomic analysis identifies the S100 calcium-binding protein β subunit (S100B) and intercellular adhesion molecule-1 (ICAM-1) as potential diagnostic biomarkers for acute cerebral infarction. [J]. Genes & Diseases 1(1):46-48(2024)
DOI：

Dan Cheng, Yushuo Wang, Jingna Li, et al. Transcriptomic analysis identifies the S100 calcium-binding protein β subunit (S100B) and intercellular adhesion molecule-1 (ICAM-1) as potential diagnostic biomarkers for acute cerebral infarction. [J]. Genes & Diseases 1(1):46-48(2024) DOI： 10.1016/j.gendis.2023.03.006.

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1 J. Tao, S. Yin, Y. Song, et al.Novel scorpion venom peptide HsTx2 ameliorates cerebral ischemic brain injury in rats via the MAPK signaling pathway Biochem Biophys Res Commun, 534 (2021), pp. 442-449

2 F. Purroy, J. Farré-Rodriguez, G. Mauri-Capdevila, et al.Basal IL-6 and S100b levels are associated with infarct volume Acta Neurol Scand, 144 (5) (2021), pp. 517-523

3 X. Zhang, F. Zhou, W. Wang, et al.Levels of adhesion molecules and clinical outcomes in patients with ischemic stroke after mechanical thrombectomy Front Neurol, 13 (2022), p. 1024162

4 F. Michetti, N. D'Ambrosi, A. Toesca, et al.The S100B story: from biomarker to active factor in neural injury J Neurochem, 148 (2) (2019), pp. 168-187

5 E. Hayakawa, T. Yoshimoto, N. Sekizawa, et al.Overexpression of receptor for advanced glycation end products induces monocyte chemoattractant protein-1 expression in rat vascular smooth muscle cell line J Atherosclerosis Thromb, 19 (1) (2012), pp. 13-22

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