C19MC miRNA-520G induces <em>SP100</em> antiviral gene transcription and inhibits melanin production in skin cutaneous melanoma

Goodwin G. Jinesh; Marian T. Smallin; Nino Mtchedlidze; Isha Godwin; Marco Napoli; Nicole Hackel; Manali S. Phadke; Avani A. Deshpande; Xiaobo Li; John H. Lockhart; Jaden R. Baldwin; Suehelay Acevedo-Acevedo; Yifeng Gao; Michelle A. Reiser; Keiran S.M. Smalley; Elsa R. Flores; Andrew S. Brohl

doi:10.1016/j.gendis.2023.02.047

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C19MC miRNA-520G induces SP100 antiviral gene transcription and inhibits melanin production in skin cutaneous melanoma

Short communication | 更新时间：2024-02-04

- C19MC miRNA-520G induces SP100 antiviral gene transcription and inhibits melanin production in skin cutaneous melanoma
- Genes & Diseases Vol. 1, Issue 1, Pages: 60-63(2024)
- 作者机构：
  
  1. Department of Molecular Oncology, H. Lee Moffitt Cancer Center & Research Institute,FL,Tampa,USA,33612
  2. Molecular Medicine Program, H. Lee Moffitt Cancer Center & Research Institute,FL,Tampa,USA,33612
  3. Saveetha Medical College,, Tamil Nadu,Chennai,India,602105
  4. Tumor Biology Department, H. Lee Moffitt Cancer Center & Research Institute,FL,Tampa,USA,33612
  5. Sarcoma Department, H. Lee Moffitt Cancer Center & Research Institute,FL,Tampa,USA,33612
- 作者简介：
- 基金信息：
- DOI：10.1016/j.gendis.2023.02.047
  CLC：
- Published：2024，
  
  Published Online：1 January 2024，
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Goodwin G. Jinesh, Marian T. Smallin, Nino Mtchedlidze, et al. C19MC miRNA-520G induces SP100 antiviral gene transcription and inhibits melanin production in skin cutaneous melanoma. [J]. Genes & Diseases 1(1):60-63(2024)
DOI：

Goodwin G. Jinesh, Marian T. Smallin, Nino Mtchedlidze, et al. C19MC miRNA-520G induces SP100 antiviral gene transcription and inhibits melanin production in skin cutaneous melanoma. [J]. Genes & Diseases 1(1):60-63(2024) DOI： 10.1016/j.gendis.2023.02.047.

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1 T. Grötzinger, T. Sternsdorf, K. Jensen, et al.Interferon-modulated expression of genes encoding the nuclear-dot-associated proteins Sp100 and promyelocytic leukemia protein (PML) Eur J Biochem, 238 (2) (1996), pp. 554-560

2 E. Delorme-Axford, R.B. Donker, J.F. Mouillet, et al.Human placental trophoblasts confer viral resistance to recipient cells Proc Natl Acad Sci U S A, 110 (29) (2013), pp. 12048-12053

3 M. Harel, R. Ortenberg, S.K. Varanasi, et al.Proteomics of melanoma response to immunotherapy reveals mitochondrial dependence Cell, 179 (1) (2019), pp. 236-250

4 G.G. Jinesh, M. Napoli, H.D. Ackerman, et al.Regulation of MYO18B mRNA by a network of C19MC miRNA-520G, IFN-γ, CEBPB, p53 and bFGF in hepatocellular carcinoma Sci Rep, 10 (1) (2020), p. 12371

5 G.G. Jinesh, M. Napoli, M.T. Smallin, et al.Mutant p53s and chromosome 19 microRNA cluster overexpression regulate cancer testis antigen expression and cellular transformation in hepatocellular carcinoma Sci Rep, 11 (2021), p. 12673

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