Histone demethylase Kdm5c regulates osteogenesis and bone formation via PI3K/Akt/HIF1α and Wnt/β-catenin signaling pathways

Ying Li; Lingli Ding; Yage Zhang; Bingyu Zhou; Gene Chi Wai Man; Min Wang; Jinglan Li; Yamei Liu; Weiping Lin; Haibin Wang; Sien Lin; Liangliang Xu

doi:10.1016/j.gendis.2023.02.041

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Histone demethylase Kdm5c regulates osteogenesis and bone formation via PI3K/Akt/HIF1α and Wnt/β-catenin signaling pathways

Short communication | 更新时间：2024-02-04

- Histone demethylase Kdm5c regulates osteogenesis and bone formation via PI3K/Akt/HIF1α and Wnt/β-catenin signaling pathways
- Genes & Diseases Vol. 1, Issue 1, Pages: 64-66(2024)
- 作者机构：
  
  1. Key Laboratory of Orthopaedics & Traumatology, Lingnan Medical Research Center, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou University of Chinese Medicine,Guangdong,Guangzhou,China,510000
  2. Department of Orthopaedics & Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin,Hong Kong SAR,China,999077
  3. Departments of Diagnostics of Traditional Chinese Medicine, Guangzhou University of Chinese Medicine,Guangdong,Guangzhou,China,510000
  4. Orthopaedic Research Lab, Affiliated Hospital of Guangdong Medical University, Guangdong Medical University,Guangdong,Zhanjiang,China,524001
- 作者简介：
- 基金信息：
- DOI：10.1016/j.gendis.2023.02.041
  CLC：
- Published：2024，
  
  Published Online：1 January 2024，
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Ying Li, Lingli Ding, Yage Zhang, et al. Histone demethylase Kdm5c regulates osteogenesis and bone formation via PI3K/Akt/HIF1α and Wnt/β-catenin signaling pathways. [J]. Genes & Diseases 1(1):64-66(2024)
DOI：

Ying Li, Lingli Ding, Yage Zhang, et al. Histone demethylase Kdm5c regulates osteogenesis and bone formation via PI3K/Akt/HIF1α and Wnt/β-catenin signaling pathways. [J]. Genes & Diseases 1(1):64-66(2024) DOI： 10.1016/j.gendis.2023.02.041.

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3 Y. Hou, W. Lin, Y. Li, et al.De-osteogenic-differentiated mesenchymal stem cells accelerate fracture healing by mir-92b J Orthop Transl, 27 (2021), pp. 25-32

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5 Y. Rui, L. Xu, R. Chen, et al.Epigenetic memory gained by priming with osteogenic induction medium improves osteogenesis and other properties of mesenchymal stem cells Sci Rep, 5 (2015), Article 11056

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