Skp2 is a novel regulator of LSD1 expression and function in gastric cancer

Moges Dessale Asmamaw; Li-Rong Zhang; Hong-Min Liu; Xiao-Jing Shi; Ying Liu

doi:10.1016/j.gendis.2023.01.015

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Skp2 is a novel regulator of LSD1 expression and function in gastric cancer

Short communication | 更新时间：2024-02-04

- Skp2 is a novel regulator of LSD1 expression and function in gastric cancer
- Genes & Diseases Vol. 1, Issue 6, Pages: 2267-2269(2023)
- 作者机构：
  
  1. Department of Pharmacology, School of Basic Medical Sciences, State Key Laboratory for Esophageal Cancer Prevention and Treatment, Zhengzhou University,Henan,Zhengzhou,China,450001
  2. School of Pharmaceutical Sciences, Zhengzhou University,Henan,Zhengzhou,China,450001
  3. Key Laboratory of Advanced Drug Preparation Technologies, Ministry of Education of China,Henan,Zhengzhou,China,450001
  4. Academy of Medical Sciences, Zhengzhou University,Henan,Zhengzhou,China,450052
  5. Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University,Henan,Zhengzhou,China,450052
  6. Henan Engineering Research Center for Application & Translation of Precision Clinical Pharmacy,Henan,Zhengzhou,China,450052
- 作者简介：
- 基金信息：
- DOI：10.1016/j.gendis.2023.01.015
  CLC：
- Published：2023，
  
  Published Online：1 November 2023，
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Moges Dessale Asmamaw, Li-Rong Zhang, Hong-Min Liu, et al. Skp2 is a novel regulator of LSD1 expression and function in gastric cancer. [J]. Genes & Diseases 1(6):2267-2269(2023)
DOI：

Moges Dessale Asmamaw, Li-Rong Zhang, Hong-Min Liu, et al. Skp2 is a novel regulator of LSD1 expression and function in gastric cancer. [J]. Genes & Diseases 1(6):2267-2269(2023) DOI： 10.1016/j.gendis.2023.01.015.

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1 M.D. Asmamaw, Y. Liu, Y.C. Zheng, et al.Skp2 in the ubiquitin-proteasome system: a comprehensive review Med Res Rev, 40 (5) (2020), pp. 1920-1949

2 C.H. Chan, S.W. Lee, C.F. Li, et al.Deciphering the transcriptional complex critical for RhoA gene expression and cancer metastasis Nat Cell Biol, 12 (5) (2010), pp. 457-467

3 N. von der Lehr, S. Johansson, S. Wu, et al.The F-box protein Skp2 participates in c-Myc proteosomal degradation and acts as a cofactor for c-Myc-regulated transcription Mol Cell, 11 (5) (2003), pp. 1189-1200

4 F. Faiola, X. Liu, S. Lo, et al.Dual regulation of c-Myc by p300 via acetylation-dependent control of Myc protein turnover and coactivation of Myc-induced transcription Mol Cell Biol, 25 (23) (2005), pp. 10220-10234

5 M. Nagasaka, K. Tsuzuki, Y. Ozeki, et al.Lysine-specific demethylase 1 (LSD1/KDM1A) is a novel target gene of c-Myc Biol Pharm Bull, 42 (3) (2019), pp. 481-488

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