Biology-related disciplines in medical school of comprehensive university are cur-rently confronted with some difficulties， including unclear position and indistinguishable characteris-tics. In this paper， we proposed that biology-related disciplines in medical school of comprehensive university should center on disease research， emphasize medical feature and give full play to its tech-nical advantage thus to provide technical support for basic medicine and clinical medicine. Mean-while， sources of multiple disciplines should be effectively integrated by breaking through the limitation of discipline and administrative system. An interdisciplinary molecular medicine platform was built up for researching and teaching.