Organic phosphorus pesticide poisoning is a common disease in emergency. Com pared with other clinical disease teaching， the basic concepts and theories of this unit are relatively less and more fixed， which is conducive to the case based learning（CBL）. The CBL teaching curricu lum of organic phosphorus pesticide poisoning includes three aspects： pre class teaching design， class room teaching， after class teaching evaluation and feedback. Pre class teaching requires teachers to carefully read the syllabus， choose the teaching content， and design typical cases and problems. Classroom teaching emphasizes a lively and relaxed atmosphere， Teachers should guide students to think about questions and find answers themselves， and cultivated the correct clinic ideation through the combination of their theoretical knowledge and clinical practice in a classroom environment. Teaching evaluation and feedback help teachers to summarize what they are teaching and promote the teaching， which benefits both the teachers and students.