Objective　To explore the application effect of magnetic resonance imaging (MRI) sequence experiment based on virtual simulation software in undergraduate teaching of medical imaging technology. Methods　Fifty-six undergraduate students from the Batch 2015 and Batch 2016 medical imaging technology of West China Clinical Medical College of Sichuan University were recruited in this study. They were divided into 2 groups: experimental group (Batch 2016) and control group (Batch 2015). The experimental group adopted the teaching method based on virtual simulation experiment

and the control group used the teaching method based on traditional small-sized magnetic resonance. The after-class test scores and final exam scores of the two groups of students were compared

and the questionnaire survey on teaching effectiveness was conducted for students in the experimental group SPSS 21.0 was used for t test and Mann-Whitney U test. Results The scores of theoretical knowledge and the final grades in the experimental group were significantly higher than those of the control group [(84.55 ± 6.57) points vs. (79.37 ± 6.13) points; (90.03 ± 4.72) points vs. (80.06 ± 7.29) points

all P < 0.05). The effective recovery rate of the questionnaires was 100%

and the questionnaire survey showed that the experimental group was significantly superior to the control group in such four aspects as increasing subject interest

expanding relevant knowledge

solving clinical work

and promoting teamwork (P < 0.05). Conclusion　In MRI sequence teaching

the teaching method based on virtual simulation software can increase the students' interests in learning

strengthen their understanding of MRI principles

then effectively improve the teaching effect of medical imaging undergraduate education.