Objective　To explore the implementation method of case teaching in pharmacology teaching according to the standards of golden course. Methods　The students from Batch 2017 clinical medical students in our university were selected as the research objects

and randomized into the control group (n=121) and the case teaching group (n=171). The control group used online learning and traditional lecture

and the case teaching group adopted the online teaching and case teaching methods. And the teaching effect was evaluated by questionnaire survey and final performance analysis． Results　Compared with control group，the case teaching group had better final performance (P<0.01). The questionnaire survey showed that the case teaching improved the learning interest of students and also enhanced their application ability of the knowledge (P<0.01 or P<0.05). Conclusion　Case teaching has achieved good teaching effect in pharmacology teaching.