Objective　To explore the effect of the X-BL mixed teaching mode on Pharmacology course. Methods　In Pharmacology course of the 2017 pharmacy major of our university

3 teaching units were randomly selected as the control group while the rest 3 teaching units were selected as the experimental group. Traditional teaching mode was carried out in control group. In the experimental group

we designed a X-BL mixed teaching mode composed of web-based learning (WBL)

case-based learning (CBL)

and team-based learning (TBL). Teaching effects of the two groups were compared using online unit tests and questionnaires. Test scores were analyzed by SPSS 20.0

and differences between groups were analyzed by t test. Results　The test scores of each unit of the experimental group were significantly higher than those of the control group (P<0.01)

and the low scores were all zeroed. The questionnaires showed that the two groups showed similar learning willingness

but the experimental group students were more satisfied with teaching method

teaching quality

classroom atmosphere

teacher guidance and learning effect than the control group. Conclusion　The X-BL mixed teaching mode

which focused on case teaching and group learning

integrated online and offline teaching

and information teaching

has showed a better teaching effect than traditional teaching in the Pharmacology courses. This teaching mode may have certain promotion value in the future teaching applications.