MEASUREMENT OF LEFT VENTRICULAR PUMP FUNCTION OF RATS WITH ELECTROMAGNETIC FLOWMETER

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- MEASUREMENT OF LEFT VENTRICULAR PUMP FUNCTION OF RATS WITH ELECTROMAGNETIC FLOWMETER
- Journal of Chongqing Medical University Issue 4, Pages: 246-249(1984)
- 作者机构：
  
  1. 重庆医学院病理生理教研室
  2. 西安医学院病理生理教研室
  3. 重庆医学院病理生理教研室西安医学院病理生理教研室
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：1984，
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[1]杜晓军,高广道.大鼠左心室泵功能的电磁流量计测定[J].重庆医学院学报,1984(04):246-249.

Department of Pathophysiology Du XiaojunDepartment of Pathophysiology Xian Medical College Gao Guangdao. MEASUREMENT OF LEFT VENTRICULAR PUMP FUNCTION OF RATS WITH ELECTROMAGNETIC FLOWMETER. [J]. Journal of Chongqing Medical University (4):246-249(1984)
[1]杜晓军,高广道.大鼠左心室泵功能的电磁流量计测定[J].重庆医学院学报,1984(04):246-249. DOI：

Department of Pathophysiology Du XiaojunDepartment of Pathophysiology Xian Medical College Gao Guangdao. MEASUREMENT OF LEFT VENTRICULAR PUMP FUNCTION OF RATS WITH ELECTROMAGNETIC FLOWMETER. [J]. Journal of Chongqing Medical University (4):246-249(1984) DOI：

<正> 大鼠是心血管系统生理、药理和病理生理实验研究的常用动物

因而大鼠各项心功能指标测定方法的建立很受重视。泵功能是血液动力学的重要指标

测定大鼠泵功能的方法很多

自1972年以来国外陆续有应用电磁流量计测定大鼠心输出量（CO）的文献

但国内至今未见到这方面的资料

而且很少见到在增加容量负荷时正常大鼠泵功能变化的报道。本文报道应用电磁流量计测

The indices of left ventricular pump function were measured with electromagnetic flowmeter in 38 anesthetized

open chest rats with artificial ventilation.The results were as follows:CI 225±5 ml/min/kg (M±SE)

SVI 0.48±0.01ml/kg

AFVmax 3.34±0.02ml/s

dF/dTmax 176±6 ml/s~2.The physiological status of the model within 60 minutes was stable.With increasing of left ventricular preload

CI increased to 619±6 ml/min/kg (increased by 177±6% over beseline CI)

reflecting the maximun diastolic cardiac reserve.The results furnished here may be useful in experiments.

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