Effects of cisapride on gallbladder emptying in the healthy volunteers

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Effects of cisapride on gallbladder emptying in the healthy volunteers

更新时间：2024-01-17

- Effects of cisapride on gallbladder emptying in the healthy volunteers
- Journal of Chongqing Medical University Issue 2, Pages: 179-180(2001)
- 作者机构：
  
  1. 重庆医科大学临床学院消化内科,重庆,400016
  2. 重庆医科大学临床学院B超室,重庆,400016
- 作者简介：
- 基金信息：
- DOI：
  CLC： R969
- Published：2001，
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[1]张霞,唐承薇,钟晓明.西沙必利对健康志愿者胆囊排空的作用[J].重庆医科大学学报,2001(02):179-180.

Effects of cisapride on gallbladder emptying in the healthy volunteers. [J]. Journal of Chongqing Medical University (2):179-180(2001)
[1]张霞,唐承薇,钟晓明.西沙必利对健康志愿者胆囊排空的作用[J].重庆医科大学学报,2001(02):179-180. DOI：

Effects of cisapride on gallbladder emptying in the healthy volunteers. [J]. Journal of Chongqing Medical University (2):179-180(2001) DOI：

摘要

目的：了解西沙必利对健康人类胆囊张力及餐后胆囊排空的影响。方法：应用B型超声仪测定了15 例健康志愿者服用西沙必利前后的空腹和餐后的胆囊容积，并计算其对胆囊排空率的影响。结果：15例健康志愿者口服西沙必利前、后空腹胆囊的容积无明显改变（Ｐ＞0.05）。服用西沙必利后的餐后30min胆囊容积较服西沙必利前明显缩小（Ｐ＜0.05）。服西沙必利后胆囊排空率显著增加（Ｐ＜0.001）。结论：西沙必利对空腹胆囊容积无明显影响，但可显著促进餐后胆囊的收缩及排空。

Abstract

Objective: To study effects of cisapride on the human gallbladder volume and emptying. Methods: Fasting and postprandial gallbladder volumes were measured with ultrasonography in 15 healthy volunteers before and after taking cisapride orally. Gallbladder volumes were normalized to gallbladder ejection frequency (GBEF). Results: The fasting gallbladder volume in 15 healthy subjects did not change before or after cisapride administration (Ｐ>0.05). Postprandial gallbladder volume 30min after taking became smaller than that before taking cisapride (Ｐ<0.05). GBEF was significantly enhanced that after cisapride administration(Ｐ<0.001). Conclusion: Cisapride had no effect on the fasting gallbladder volumes but significantly promoted postprandial gallbladder contraction and emptying.

关键词

西沙必利胆囊容积胆囊排空

Keywords

CisaprideGallbladder volumeGallbladder emptying

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Department of Gastroenterology, College of Clinical Medicine, Chongqing Medical University

重庆医科大学临床学院超声科

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