Objective: Chemotherapy regimen of CHOP was used in the treatment of Non-Hodgkin lymphoma(NHL). On the basis of it we added THP instead of ADM to improve effectiveness of the treatment on NHL. Method: With the chemotherapy regimen of COTP
we treated 23 patients with NHL during the period from January
1995 to July
2000. Results: For these 23 patients with NHL
the total rate of remission reached 78.2%. The toxicity and side effect of COTP were less severe than those seen in the CHOP. Conclusion: This study suggested that COTP is an effective chemotherapy regimen with less severe toxicity and side effect.