A study on the levels of sICAM-1 and IL-12 in serum of patients with respiratory failure typeⅡ

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A study on the levels of sICAM-1 and IL-12 in serum of patients with respiratory failure typeⅡ

更新时间：2024-01-17

- A study on the levels of sICAM-1 and IL-12 in serum of patients with respiratory failure typeⅡ
- Journal of Chongqing Medical University Issue 3, Pages: 322-323(2002)
- 作者机构：
  
  1. 重庆医科大学第二临床学院呼吸科
  2. 重庆医科大学第二临床学院内分泌研究室,重庆,400010
- 作者简介：
- 基金信息：
- DOI：
  CLC： R563.8
- Published：2002，
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[1]王导新,庞久高.Ⅱ型呼吸衰竭急性加重期患者血清sICAM-1及IL-12变化的探讨[J].重庆医科大学学报,2002(03):322-323.

A study on the levels of sICAM-1 and IL-12 in serum of patients with respiratory failure typeⅡ. [J]. Journal of Chongqing Medical University (3):322-323(2002)
[1]王导新,庞久高.Ⅱ型呼吸衰竭急性加重期患者血清sICAM-1及IL-12变化的探讨[J].重庆医科大学学报,2002(03):322-323. DOI：

A study on the levels of sICAM-1 and IL-12 in serum of patients with respiratory failure typeⅡ. [J]. Journal of Chongqing Medical University (3):322-323(2002) DOI：

摘要

目的:为了探讨Ⅱ型呼吸衰竭急性加重期患者血清及的动态变化。sICAM-1IL-12方法:动态观察例Ⅱ型呼吸衰31竭急性加重期患者及例哮喘发作期患者治疗前后血清及变化情况

采用双抗体夹心法测定。20sICAM-1IL-12ELISA结果:Ⅱ型呼吸衰竭急性加重期及哮喘发作期患者治疗前血清水平明显高于健康组

差异有显著性（sICAM-1p<）

治疗后均较0.01前有所下降

但均高于正常

变化无显著性。IL-12结论:血清及变化对判断Ⅱ型呼吸衰竭急性加重期患者病情sICAM-1IL-12轻重、估计预后及了解机体免疫病理过程有重要意义。

Abstract

Objective: To explore the change of the levels of sICAM-1 and IL-12 in serum of the patients with Ⅱrespiratory failure type . Methods: The levels of sICAM-1 and IL-12 in serum were measured by sandwiched ⅡELISA in 31 patients with respiratory failure type and 20 patients with acute asthma. Results: The levels of ⅡsICAM-1 were higher in patients with respiratory failure type and patients with acute asthma than that in (normal controlsp)<0.01

It cloud be reduced after the treatment. No change of the levels of IL-12 was observed in both groups. Conclusion: The findings suggest that sICAM-1 and IL-12 in serum may be an important Ⅱreferential indicator for monitoring and predicting in patients with respiratory failure type .

关键词

可溶性细胞间粘附分子-1白细胞介素-12血清Ⅱ型呼吸衰竭

Keywords

sICAM-1IL-12serumRespiratory failure type

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