Detection of antibody in serum and cerebrospinal fluid of children Japanese  encephalitis

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Detection of antibody in serum and cerebrospinal fluid of children Japanese encephalitis

更新时间：2024-01-17

- Detection of antibody in serum and cerebrospinal fluid of children Japanese encephalitis
- Journal of Chongqing Medical University Issue 4, Pages: 456-457(2002)
- 作者机构：
  
  重庆医科大学儿科学院感染消化科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：
  CLC： R446.62
- Published：2002，
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[1]黄延风,朱朝敏,赵瑞秋,张爱华.儿童流行性乙型脑炎血清和脑脊液抗体检测的研究[J].重庆医科大学学报,2002(04):456-457.

Detection of antibody in serum and cerebrospinal fluid of children Japanese encephalitis. [J]. Journal of Chongqing Medical University (4):456-457(2002)
[1]黄延风,朱朝敏,赵瑞秋,张爱华.儿童流行性乙型脑炎血清和脑脊液抗体检测的研究[J].重庆医科大学学报,2002(04):456-457. DOI：

Detection of antibody in serum and cerebrospinal fluid of children Japanese encephalitis. [J]. Journal of Chongqing Medical University (4):456-457(2002) DOI：

摘要

目的：探讨流行性乙型脑炎时血清和脑脊液乙脑抗体IgM（抗JEV-IgM）检测的诊断价值。方法：采用抗体捕获法测定182例乙脑住院病人血清和脑脊液抗JEV-IgM，并分析它与病程、年龄、病型的关系。结果：乙脑病人血清和脑脊液抗JEV-IgM检出的阳性率分别为61.87%、86.67%，且后者明显高于前者（P<0.005）；不同病程、年龄、病型血清和脑脊液抗JEV-IgM的阳性率无显著差异（P>0.05）。结论：用抗体捕获法检测血清和脑脊液抗JEV-IgM对流行性乙型脑炎有早期诊断的价值，且该方法特异性高、敏感性强。

Abstract

Objective: To observe the value of detection of JEV-IgM in serum and cerebrospinal fluid for diagnosis of Japanese encephalitis. Methods: JEV-IgM in serum and cerebrospinal fluid were detected by antibody capture method in 182 in-patients with Japanese encephalitis and the relationship between JEV-IgM and duration

age

type of disease was analyzed. Results: The positive rate of JEV-IgM in serum and cerebrospinal fluid were 61.87% and 86.67% respectively with Japanese encephalitis; the latter was significantly higher than the former ( P<0.005); the positive rate of JEV-IgM in serum and cerebrospinal fluid were not markedly different in different duration

age

and type of disease (P>0.05). Conclusion:The determination of JEV-IgM in serum and cerebrospinal fluid with antibody capture method can be used to help the early diagnosis of Japanese encephalitis. The method has best sensitivity and specificity.

关键词

儿童乙型脑炎血清、脑脊液抗JEV-IgM

Keywords

childrenJapanese encephalitisSerum and cerebrospinal fluid JEV-IgM

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