Susceptibility testing and strain identification of Candida species

ZHOU Xun; et al

您当前的位置：

首页 >

文章列表页 >

Susceptibility testing and strain identification of Candida species

更新时间：2024-01-17

- Susceptibility testing and strain identification of Candida species
- Journal of Chongqing Medical University Issue 4, Pages: 425-427(2007)
- 作者机构：
  
  1. 重庆医科大学附属第一医院皮肤性病科
  2. 重庆医科大学附属第一医院皮肤性病科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：
  CLC： R446.5
- Published：2007，
扫描看全文
[1]周汛,李桂明.110株念珠菌的菌种鉴定及药敏试验[J].重庆医科大学学报,2007(04):425-427.

ZHOU Xun, et al. Susceptibility testing and strain identification of Candida species. [J]. Journal of Chongqing Medical University (4):425-427(2007)
[1]周汛,李桂明.110株念珠菌的菌种鉴定及药敏试验[J].重庆医科大学学报,2007(04):425-427. DOI：

ZHOU Xun, et al. Susceptibility testing and strain identification of Candida species. [J]. Journal of Chongqing Medical University (4):425-427(2007) DOI：

摘要

目的:了解我院皮肤、粘膜念珠菌感染的菌种分布及其对两性霉素B、酮康唑、咪康唑、伊曲康唑、氟康唑、5-氟胞嘧啶及特比奈芬的体外敏感性。方法:收集临床110株念珠菌标本

采用科玛嘉显色培养基及API20C鉴定菌种

微量稀释念珠菌药敏试剂板检测其药物敏感性。结果:110株真菌中白色念珠菌94株

热带念珠菌6株

克柔念珠菌4株

光滑念珠菌4株

近平滑念珠菌2株。对酮康唑、咪康唑、伊曲康唑、氟康唑、5-氟胞嘧啶及特比奈芬的耐药率分别为0%、18.28%、1.81%、5.45%、3.63%及94.55%。结论:我院念珠菌感染仍以白念珠菌为主

对常用抗真菌药物呈不同程度的耐药

应建立真菌常规菌种鉴定及药敏试验

指导临床合理用药。

Abstract

Objective:To identify the strain and to study the in-vitro susceptibilities of Candida species collected from clinical samples of skin and mucosa to Amphotericin B

Ketoconazole

Miconazole

Itraconazole

Fluconazole

5-Flucytosine and Terbinafin. Methods:110 clinical isolates of yeasts were identified by CHROMAGAR and API20C

meanwhile

the susceptibility to six antifungal drugs was examined by microdilution method using Sensititre Yeast One panels. Results:There were 94 C.albicans

6 C.tropicalis

4 C.krusei

4 C.glabrata

and 2 C.parapsilosis among 110 isolates of yeasts.There were 0.91%

1.81%

18.28%

1.81%

5.45%

3.63% and 94.55% of isolates displaying resistance to Amphotericin B

Ketoconazole

Miconazole

Itraconazole

Fluconazole

5-Flucytosine and Terbinafin

respectively.Conclusions:C.albicans is the main infection strain in our hospital

and candida species display different resistance to six antifungal drugs. It is necessary to test strain identification and susceptibility of candida species to guild the rational clinical drug use.

关键词

念珠菌菌种鉴定药敏试验

Keywords

Candida speciesStrain identificationSusceptibility testing

references

Views

179

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

No data

Related Author

No data

Related Institution

No data

⁰