Objective:To investigate different region’s bone mineral density(BMD)changing pattern in female adults in Chongqing area

evaluate the value of different sites in the diagnosis of primary osteoporosis

and provide scientific basis for diagnosis and prevention of osteoporosis.Methods:1435 female adults in Chongqing area were randomly selected.The assessment of BMD in spine region was performed among 1345 female adults with NORLAND XR-46 dual-energy X-ray absorptiometer.BMD of the proximal femur in 308 was measured.All data was processed by relative statistics analysis.Results:BMD change of Wards Tri area occured 5 years earlier than that of others and it decreased obviously.It was the most sensitive site to reflect the BMD change.BMD of each site correlated with those of other sites.A cubic regression model was the better model to establish a normal BMD reference curve.R square of cubic regression curve was maximum value.R square in femoral neck and Wards triangle were larger than that of other sites.There was no significant difference in the incidence rate of osteoporosis in different sites.Conclusions:We should choose different sites to diagnose osteoporosis in different age groups.BMD of proximal femur should be measured in female adults less than 50 years

while BMD of proximal femur and lumbar spine should be measured in female adults older than 50 years.