Therapeutic effect of minocycline hydrochloride in treatment of chronic periodontitis

HUANG Lin-xian

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Therapeutic effect of minocycline hydrochloride in treatment of chronic periodontitis

更新时间：2024-01-17

- Therapeutic effect of minocycline hydrochloride in treatment of chronic periodontitis
- Journal of Chongqing Medical University Issue 2, Pages: 229-230(2008)
- 作者机构：
  
  重庆市江北区第一人民医院口腔科,重庆,400017
- 作者简介：
- 基金信息：
- DOI：
  CLC： R781.4
- Published：2008，
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[1]黄临宪.盐酸米诺环素软膏治疗慢性牙周炎的疗效观察[J].重庆医科大学学报,2008(02):229-230+247.

HUANG Lin-xian. Therapeutic effect of minocycline hydrochloride in treatment of chronic periodontitis. [J]. Journal of Chongqing Medical University (2):229-230(2008)
[1]黄临宪.盐酸米诺环素软膏治疗慢性牙周炎的疗效观察[J].重庆医科大学学报,2008(02):229-230+247. DOI：

HUANG Lin-xian. Therapeutic effect of minocycline hydrochloride in treatment of chronic periodontitis. [J]. Journal of Chongqing Medical University (2):229-230(2008) DOI：

摘要

目的:评价盐酸米诺环素软膏治疗慢性牙周炎的临床疗效。方法:选择临床上诊断为慢性牙周炎的患者75人

共150颗患牙

按就诊顺序

分为试验组（75例牙用盐酸米诺环素软膏）和对照组（75例牙用20g/L碘甘油）

试验前后检查牙龈指数和牙周袋深度

结合临床症状进行综合评价。结果:试验前两组基线资料具有均衡性。用药4周后

试验组牙龈指数和牙周袋深度明显好转

临床疗效综合评价

试验组优于对照组

差别有统计学意义（P<0.05）。结论:盐酸米诺环素软膏治疗慢性牙周炎疗效显著

具有一定的临床运用价值。

Abstract

Objective:To evaluate the therapeutic effect of minocycline hydrochloride on chronic periodontitis.Methods:150 teeth of 75 patients dagnosed as chronic periodontitis were divided as test group(75 teeth treated by minocycline hydrochloride) and control group(75 teeth treated by 20g/L iodoglycerin).The effect of medicines were evaluated by clinical symptom combined with gingival index and the depth of pocket which were examined before and after treatment.Results:The baseline data of two groups indicated equilibrium.The status aroud the tested teeth in test group were improved

which was better than control group after 4-week treatment.The therapeutic effect of minocycline hydrochloride was better than iodoglycerin and there was statistic difference(P<0.05).Conclusion:Minocycline hydrochloride shows significant effect on chronic periodontitis.

关键词

盐酸米诺环素软膏慢性牙周炎疗效

Keywords

Minocycline hydrochloridechronic periodontitistherapeutic effect

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