Imaging study of MRI-guided high intensity focused ultrasound damage of liver tissues in vitro

SHEN Jie; et al

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Imaging study of MRI-guided high intensity focused ultrasound damage of liver tissues in vitro

更新时间：2024-01-17

- Imaging study of MRI-guided high intensity focused ultrasound damage of liver tissues in vitro
- Journal of Chongqing Medical University Issue 8, Pages: 907-910(2008)
- 作者机构：
  
  重庆医科大学医学超声工程研究所
- 作者简介：
- 基金信息：
- DOI：
  CLC： R735.7
- Published：2008，
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[1]沈洁,邹建中,申俊玲,刘映江,胡晓,董洁,王智彪.MRI监控高强度聚焦超声损伤离体肝脏的影像学研究[J].重庆医科大学学报,2008(08):907-910.

SHEN Jie, et al. Imaging study of MRI-guided high intensity focused ultrasound damage of liver tissues in vitro. [J]. Journal of Chongqing Medical University (8):907-910(2008)
[1]沈洁,邹建中,申俊玲,刘映江,胡晓,董洁,王智彪.MRI监控高强度聚焦超声损伤离体肝脏的影像学研究[J].重庆医科大学学报,2008(08):907-910. DOI：

SHEN Jie, et al. Imaging study of MRI-guided high intensity focused ultrasound damage of liver tissues in vitro. [J]. Journal of Chongqing Medical University (8):907-910(2008) DOI：

摘要

目的:观察高强度聚焦超声（High intensity focused ultrasound

HIFU）损伤离体肝组织的MRI监控图像变化

探讨MRI监控的有效性和准确性。方法:通过MRI监控HIFU辐照离体牛肝组织

观察不同剂量损伤灶的MRI图像

以及与实际损伤面积的关系。结果:本研究共计60例损伤灶

其中50例（83.3%）损伤灶于PDWI和T2WI中表现为边界清晰的稍低信号

与实际损伤面积比较无统计学差异（P>0.05）。而在T1WI中仅23例（38.3%）可见信号增高。结论:本研究证实我所自行研制的MRI监控HIFU设备能有效监控治疗

准确评价疗效

并为后期治疗肝脏肿瘤提供一定的影像学基础。

Abstract

Objective:To observe the liver tissue in vitro damaged by high intensity focused ultrasound(HIFU)using MRI

and evaluate the validity and accuracy of MRI-guided treatment.Methods:Calf liver tissues in vitro were exposed to MRI-guided HIFU with different intensity and duration.The lesions on MRI imaging were compared with the actual necrotic foci.Results:60 lesion images were inspected

50 lesions(83.3%)on T2WI and PDWI had low signals with clear border

and the lesion area on T2WI and PDWI highly correlated with the actual necrotic area(P>0.05).But only 23 lesions(38.3%)showed high signal on T1WI.Conclusion:This research confirmed the MRI-guided HIFU equipment is useful to monitor the HIFU treatment and evaluate the curative effect accurately

which provids a basis for the latter treatment of liver tumors.

关键词

高强度聚焦超声MRI肝脏

Keywords

high intensity focused ultrasoundmagnetic resonance imagingliver

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