Objective:To retrospectively study the effect and curative effectiveness of ethanol in treating HCC with portal vein tumor thrombus(PVVT) through transcatheter fed arterial super selective infusion and super selective arterial embolization of main tumor

appraise the effect of ethanol in local treatment

in order to improve the clinical curative effects on the patients. Methods:The data of study from 86 cases of HCC with PVVT in our hospital between 2001~2004 year

to the fed artery of portal vein tumor thrombus super selective infusion ethanol or ethanol and gelfoam or ethanol and lipiodol

also through transcatheter super selective embolizing the fed arterys of main tumors including TACE or ethanol and lipiodol in 86 cases HCC. The course of observation was between 2001 and 2007year. Results:The super selective fed arterial embolization of PVVT and main tumors were successful in all cases;After treatment

ascites disappeared or obviously reduced in 66.3%(57/86) of cases

reduce in 23.2%(20/86)

did not reduce in 10.5%(9/86);After 7~10d

hepatic function obviously improve or improve in 71%(61/86)

did not obviously change in 11.6%(10/86)

lowered in 6%(5/86)

with no obvious lowering of hepatic function or hepatic function failure.The survival rates at 3

6

12

24

36months were 97.7%(84/86)

95.5%(82/86)

72.7%(62/86)

47.7%(41/86) and 16.3%(14/86) respectively. Conclusion:The therapy of ethanol through catheter super selective PVVT fed arterial infusion is safe and effective

combined with super selective TAE or TACE to the fed artery of main tumor

could obviously improve the quality of life of the patients and could improve the survival rate.