Objective:To evaluate possible differences in the serum levels of basic fibroblast growth factor(bFGF)in healthy adults of different ages and sexes in Chongqing urban field in order to provide the useful reference for the varieties of the serum bFGF level in the diseased condition. Methods:Ninety healthy people in Chongqing urban regions were selected randomly and divided into the young group(18~45 y)

the middle-aged group(46~60 y) and the old group(>60 y)

with 30 people in each group. Blood were collected from the 90 people and measured for the serum concentration of bFGF by Enzyme-linked immunosorbent as- say. Statistical analysis was then performed to see whether differences exit in values among groups. Results: The mean serum level of the bFGF in the 90 healthy human subjects was 31.24±15.80 pg/ml. The concentration of the bFGF in the old-aged group was significantly lower than those in the youth and the middle-aged group

regardless of the male and female(all P<0.05). There were no significant differences amnog other different aged-groups and sexual-groups. Conclusion:The serum level of the bFGF in the old-aged people in Chongqing urban region is significantly lower than in the youth and the middle-aged people.