Prevalent aeroallergens and sensitization risk factors in asthmatic children’s of Chongqing

CHEN Yun; et al

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Prevalent aeroallergens and sensitization risk factors in asthmatic children’s of Chongqing

更新时间：2024-01-17

- Prevalent aeroallergens and sensitization risk factors in asthmatic children’s of Chongqing
- Journal of Chongqing Medical University Vol. 34, Issue 8, Pages: 1081-1083(2009)
- 作者机构：
  
  重庆医科大学附属儿童医院呼吸中心
- 作者简介：
- 基金信息：
- DOI：
  CLC： R725.6
- Published：2009，
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[1]陈芸,黄英,罗蓉.重庆地区儿童哮喘变应原种类及致敏危险因素[J].重庆医科大学学报,2009,34(08):1081-1083.

CHEN Yun, et al. Prevalent aeroallergens and sensitization risk factors in asthmatic children’s of Chongqing. [J]. Journal of Chongqing Medical University 34(8):1081-1083(2009)
[1]陈芸,黄英,罗蓉.重庆地区儿童哮喘变应原种类及致敏危险因素[J].重庆医科大学学报,2009,34(08):1081-1083. DOI：

CHEN Yun, et al. Prevalent aeroallergens and sensitization risk factors in asthmatic children’s of Chongqing. [J]. Journal of Chongqing Medical University 34(8):1081-1083(2009) DOI：

摘要

目的:了解重庆地区儿童哮喘及相关过敏性疾病变应原种类及变应原致病相关因素。方法:标准化变应原皮肤点刺试验及问卷调查方法

对298例儿童哮喘（4～15岁）进行研究。结果:变应原总检出率为84.9%（253/298）

螨检出率最高

其次为蟑螂

第三位是猫毛;哮喘患儿阳性过敏性疾病家族史为69.6%（116/230）

而哮喘合并过敏性鼻炎占67.2%（78/116）。经多因素Logistic回归分析显示尘螨与哮喘（OR值:2.602

95%CI:1.672～7.488）发病密切相关

其致病与空调等因素显著相关（OR值:1.659

95%CI:1.139～5.942）。结论:螨是重庆地区儿童哮喘等过敏性疾病的主要变应原

空调是其致敏的重要危险因素。

Abstract

Objective:To investigate prevalent aeroallergens in ChongQing and their sensitization risk factors in children with allergic diseases

especially asthma.Methods:Skin prick tests with 13 standardized aeroallergens and questionnaires were used.A total of 298 patients

aged between 4~15 years and were diagnosed with allergic asthma and or allergic rhinitis

were investigated.Results:The total positive rate of allergen was 84.9%(253/298).The prevalence of aeroallergens were following:the first was house dust mite

cockroach followed

the third one was cat dander;the positive family history of asthma was 69.6%(116/230)

asthma and rhinitis accounted for 67.2%(78/116)。Multivariate logistic regression analyses revealed that house dust mite was an independent risk factors for asthma(odds ratio Value(OR):2.602

95%CI:1.672～7.488)

air conditioning had strong relationship with it(OR:1.659

95%CI:1.139～5.942).Conclusion:House dust mite is the major allergen of allergic diseases

especially asthma in ChongQing.Air conditioning is one of important risk factors for house dust mite sensitization.

关键词

皮肤点刺试验哮喘儿童空调

Keywords

Skin prick testsasthmachildrenAir conditioning

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Related Institution

Department of Respiratory Diseases,the Children’s Hospital,Chongqing Medical University

Department of Internal Midecine,the Children Branch,Chongqing Three Gorges Central Hospita

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Department of Pediatrics，The Affiliated Hospital of Nanjing University of Chinese Medicine，The First Clinical Medical College of Nanjing University of Chinese Medicine

Department of Respiratory Medicine，Children’s Hospital，Zhejiang University School of Medicine/ National Clinical Research Center for Child Health

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