Multi-slice spiral CT perfusion evaluation of hepatic functional reserve and surgical tolerance in patients with hepatocellular carcinoma

DU Fu-chuan; et al

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Multi-slice spiral CT perfusion evaluation of hepatic functional reserve and surgical tolerance in patients with hepatocellular carcinoma

更新时间：2024-01-17

- Multi-slice spiral CT perfusion evaluation of hepatic functional reserve and surgical tolerance in patients with hepatocellular carcinoma
- Journal of Chongqing Medical University Vol. 34, Issue 11, Pages: 1578-1580(2009)
- 作者机构：
  
  1. 海南省中医院放射科
  2. 中南大学湘雅二医院放射科
- 作者简介：
- 基金信息：
- DOI：
  CLC： R735.7
- Published：2009，
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[1]杜福川,刘辉.多层螺旋CT灌注评价肝癌患者肝储备功能及手术耐受性的意义[J].重庆医科大学学报,2009,34(11):1578-1580.

DU Fu-chuan, et al. Multi-slice spiral CT perfusion evaluation of hepatic functional reserve and surgical tolerance in patients with hepatocellular carcinoma. [J]. Journal of Chongqing Medical University 34(11):1578-1580(2009)
[1]杜福川,刘辉.多层螺旋CT灌注评价肝癌患者肝储备功能及手术耐受性的意义[J].重庆医科大学学报,2009,34(11):1578-1580. DOI：

DU Fu-chuan, et al. Multi-slice spiral CT perfusion evaluation of hepatic functional reserve and surgical tolerance in patients with hepatocellular carcinoma. [J]. Journal of Chongqing Medical University 34(11):1578-1580(2009) DOI：

摘要

目的:探讨CT灌注成像在术前评价肝癌患者肝储备功能及手术耐受性的意义。方法:收集2005年1月～2008年12月在中南大学湘雅二医院行肝叶切除的原发性肝癌患者72例资料

通过测量肝动脉灌注量、门脉灌注量、总肝灌注量、肝脏灌注指数等指标

分析肝癌CT灌注成像特点和肝储备预测性能

并与Child-Pugh分级比较。结果:原发性肝癌CT灌注显像HAP（t=10.316

P=0.000 1）和HPI（t=18.153

P=0.000 1）高灌注

而在PVP（t=15.724

P=0.000 1）、TLP（t=8.728

P=0.000 1）则呈低灌注。并且每项灌注参数都和Child-Pugh分级相关

Abstract

Objective:To evaluate the significance of CT perfusion imaging of hepatic functional reserve and surgical to lerance in patients with hepatocellular carcinoma.Methods:Retrospective analysis were used in January 2005 ~ December 2008 of 72 cases of patients with hepatectomy for primary liver cancer.CT perfusion imaging characteristics were used to evaluate liver reserves

and compared with Child-Pugh classification.Results:In CT perfusion imaging of primary liver cancer

HAP(t = 10.316

P = 0.000 1)and HPI(t = 18.153

P = 0.000 1)showed hyperperfusion

and PVP(t = 15.724

P= 0.000 1)

TLP(t = 8.728

P= 0.000 1)showed hypoperfusion.Each perfusion parameters and Child-Pugh classification have correlation.rs were 0.724(t= 6.847

P= 0.013)

-0.694(t = 6.135

P = 0.027)

-0.764(t = 8.675

P= 0.008)and 0.733(t = 7.156

P = 0.011).Respectively.Four perfusion parameters can effectively predict the hepatic functional reserve

the area under the ROC curve were 0.869(P = 0.000 1)

0.772(P = 0.000 1)

0.835(P = 0.000 1)

0.846(P = 0.000 1).HAP and the Child-Pugh can be independent predictors of hepatic functional reserve.And they have a certain degree of complementarity.Conclusion:CT perfusion imaging of primary liver cancer has a typical imaging features

which can effectively predict the hepatic functional reserve and surgical tolerance

and have some complementary with Child-Pugh

joint forecasting can improve the diagnosis performance.

关键词

原发性肝癌CT灌注成像肝储备功能手术耐受性

Keywords

primary liver cancerCT perfusion imagingHepatic functional reserveOperation tolerance

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