Primary prostatic intravascular large B cell lymphoma:A case report and literature review

XU Man1; YANG Qing-ping2; HUANG Wen-lian1; GENG Wei-pu1; CHEN Yu1; WANG Ting-ting1

您当前的位置：

首页 >

文章列表页 >

Primary prostatic intravascular large B cell lymphoma:A case report and literature review

更新时间：2024-01-17

- Primary prostatic intravascular large B cell lymphoma:A case report and literature review
- Journal of Chongqing Medical University Vol. 36, Issue 11, Pages: 1402-1404(2011)
- 作者机构：
  
  1. 重庆医科大学基础医学院病理学教研室分子医学与肿瘤研究中心
  2. 长寿区人民医院病理科
- 作者简介：
- 基金信息：
- DOI：
  CLC： R737.25
- Published：2011，
扫描看全文
[1]徐曼,杨清平,黄文炼,耿卫朴,陈瑜,王婷婷.原发于前列腺的血管内大B细胞淋巴瘤1例报道及文献复习[J].重庆医科大学学报,2011,36(11):1402-1404.

XU Man1, YANG Qing-ping2, HUANG Wen-lian1, et al. Primary prostatic intravascular large B cell lymphoma:A case report and literature review. [J]. Journal of Chongqing Medical University 36(11):1402-1404(2011)
[1]徐曼,杨清平,黄文炼,耿卫朴,陈瑜,王婷婷.原发于前列腺的血管内大B细胞淋巴瘤1例报道及文献复习[J].重庆医科大学学报,2011,36(11):1402-1404. DOI：

XU Man1, YANG Qing-ping2, HUANG Wen-lian1, et al. Primary prostatic intravascular large B cell lymphoma:A case report and literature review. [J]. Journal of Chongqing Medical University 36(11):1402-1404(2011) DOI：

摘要

目的:探讨原发于前列腺的血管内大B细胞淋巴瘤（Intravascular large B cell lymphoma

IVLBCL）的临床病理特征及治疗效果。方法:对1例原发于前列腺的IVLBCL进行组织学观察、免疫组化染色检测和临床随访

并复习了文献报道的6例前列腺IVLBCL。结果:IVLBCL累及前列腺的患者中位年龄为68岁

患者常出现下尿路阻塞症状

体检发现前列腺肥大。前列腺组织病理活检发现前列腺间质小血管内异形的淋巴样细胞增生。免疫组化染色结果显示瘤细胞表达B细胞标记物CD20和CD79α

细胞增殖核抗原Ki67阳性率较高。患者在确诊为前列腺血IVLBCL后

接受CHOP化疗或联合利妥昔单抗治疗效果较好。结论:仅累及前列腺的IVLBL患者经手术切除前列腺并结合药物化疗预后较好。

Abstract

Objective:To investigate the clinicopathological characteristics of primary prostatic intravascular large B cell lymphoma(IVLBCL) and the prognosis of the patients.Methods:One case of primary prostatic IVLBCL was studied by microscopic observation

immunohistochemistry staining and the clinical follow up.6 cases of prostatic IVLBCL reported in the literature were reviewed.Results:The median age of prostatic IVLBCL patients was 68-year-old.They often complained of progressing dysuria

and their prostatic enlargement was revealed.After the prostatectomy

the pathological biopsy revealed that dysplastic lymphoid cells proliferating in prostatic interstitial vessels.The immunohistochemistry staining revealed that tumor cells had positive expression of B cell marker CD20 and CD79α

and many tumor cells had positive expression of Ki67.After diagnosed as primary prostatic IVLBL

the patients were treated with cyclophosphamide

doxorubincin

vincristine

and prednisolone(CHOP) and/or rituximab

With the good therapeutic effect.Conclusion:The primary prostatic IVLBCL patients have good prognoses after they undergo prostatic resection and chemotherapy.

关键词

血管内大B细胞淋巴瘤前列腺前列腺切除化疗

Keywords

intravascular large B-cell lymphomaprostateprostatic resectionchemotherapy

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Comparison of the clinical efficacy of Disitamab Vedotin and postoperative chemotherapy in the treatment of HER-2 positive locally advanced urothelial carcinoma

Effect of progressive muscle relaxation training on coping style and emotion of patients with lung cancer

Tebivudine as pre-emptive treatment against hepatitis B virus reactivation in patients after chemotherapy

Research progress of breast cancer chemotherapy related HBV reactivation

ANTINEOPLASTIC DRUG SENSITIVITY TEST (MTT ASSAY) IN CHEMOTHERAPY OF GASTROINTESTINAL MALIGNANCY-A REPORT ON PRELIMINARY CLINICAL APPLICATION

Related Author

Xu Qiao

Jiang Yu

Wan Shihao

He Yunfeng

Zhang Xia

Zhang Jingping

Wang Anni

Wen Shali

Related Institution

Department of Urology，The First Affiliated Hospital of Chongqing Medical University

Department of Clinic Nursing,Xiangya Nursing School of Central South University

Department of Infectious Disease,The First Affiliated Hospital of Chongqing Medical University

Department of Gastroenterology,Yongchuan Hospital of Chongqing Medical University

Department of Infectious Disease,Yongchuan Hospital of Chongqing Medical University

⁰