Clinical value of electroencephalogram and neuroimaging in children with febrile seizures
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Clinical value of electroencephalogram and neuroimaging in children with febrile seizures
Journal of Chongqing Medical UniversityVol. 43, Issue 2, Pages: 192(2018)
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Published:2018,
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Clinical value of electroencephalogram and neuroimaging in children with febrile seizures. [J]. Journal of Chongqing Medical University 43(2):192(2018)
DOI:
Clinical value of electroencephalogram and neuroimaging in children with febrile seizures. [J]. Journal of Chongqing Medical University 43(2):192(2018)DOI:
Clinical value of electroencephalogram and neuroimaging in children with febrile seizures
Objective:To explore the clinical value of electroencephalograms(EEG) and neuroimaging(CT or MRI) in children with febrile seizures(FS). Methods:①According to clinical features,the children with FS were classified as simple febrile seizures(SFS) and complex febrile seizures(CFS). According to the follow-up results,the children with FS were classified as children with epilepsy group and children without epilepsy group. ②The initial EEGs were recoreded within two weeks after onset in 426 children with FS. And EEGs were followed up regularly. A total of 92 children with FS underwent CT and 310 underwent MRI. Chi-square test and Lo-gistic regression analysis were used to analyze the relationship between EEG,CT/MRI and types of FS,clinical features,and sec-ondary epilepsy. Results:①The abnormal cases of initial EEGs and follow-up EEGs were 71 and 138 respectively,with significant differences(P=0.000). The abnormal cases of EEG in SFS group and CFS group ranged from 22 to 26,from 49 to 112 respectively. Compared with follow-up results before and after,there was no significant difference in SFS group(P=0.102),and the difference was significant in CFS group(P=0.008). ②In the follow-up results,the abnormal rate of EEGs were significant different in SFS group (26/426) and CFS group(112/426),children with epilepsy group(97/127) and in children without epilepsy group(41/299)(P=0.001,P=0.001). ③The abnormal rate of CT/MRI were not significant different in SFS group(CT,8/92;MRI,9/310),CFS group(CT,5/92;MRI,28/310),children with epilepsy group(CT,3/16;MRI,16/110) and in children without epilepsy group(CT,10/76;MRI,21/200)(P=0.574,P=0.755,P=0.559,P=0.293). ④The abnormali-ties of CT/MRI were not correlated with the abnormalities of EEG(P=0.836,P=0.557). Conclusion:①EEG,especially the regular follow-up of EEG,has a greater clinical value for chil-dren with CFS,and is of limited value for children with SFS. ②CT/MRI has limited clinical value in neurologically normal chil-dren with FS,and the routine examination is not justified.
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