Objective：To investigate the characteristics and influencing factors of limb myodynamia in children with severe head in－jury. Methods：A retrospective analysis of 75 children with severe craniocerebral injury in the neurosurgery department of Children’s Hospital of Chongqing Medical University from 2012 to 2014 was conducted. The duration of consciousness obstacle，the time of reha－bilitation intervention and the abnormal rate of limb myodynamia were analyzed. Bonferroni-McNemar-Bowker test was used to ana－lyze the abnormal rate of myodynamia at the time points of recovery of consciousness，neurosurgery at the end of treatment，and dis－charge after 3 months. The effects of the duration of consciousness obstacle and the time of rehabilitation intervention on myodynamia and hospitalization duration of patients with rank were analyzed by rank-sum test and logistic regression. Results：The muscle abnormal rates at three time points mentioned above were 46.7%，27.9% and 16.0% respectively. Movement function damage exerted effect on myodynamia only when recovering consciousness（P=0.09）. Consciousness obstacle > 4 days were more likely to induce myodynamia abnormal at the time points of recovery of consciousness（P=0.005），neurosurgery at the end of treatment（P=0.001），and 3 months af－ter discharge（P=0.021）. Rehabilitation treatment at the end of the treatment was likely to induce myodynamia and delayed rehabili－tation would exert more serious effect on myodynamia（P=0.034）. The OR value was 0.674 and 95% confidence interval was 0.219 to 0.219 among children with short time of consciousness obstacle. The OR value was 0.437 and 95% confidence interval was 0.117 to 0.538 among children with early rehabilitation intervention. The regression model was of significant difference（P<0.05）. Con－clusion：The reasonable nursing for children with serious brain injury at early time is very important，which is consisted of con－sciousness-promoted rehabilitation and psychological interven－tion. We should promote wake at early satgeand rehabilitation.