Objective：To comparatively analysis the treatment effects of three minimally invasive surgical approaches for great saphenous vein varicosity（GSVV）. Methods：To retrospective analysis 248 cases GSVV from January 2008 to January 2011. All samples were respectively treated by new minimally invasive stripper（NMIS，103 cases），endovenous laser ablation （EVLA，87 cases） or transilluminated powered phlebectomy （TIPP，58 cases）；It was compared each group that the hospitalization fee、amount of bleeding、mean length of hospital stay、time of surgery、postoperative complications and skin ulcers drying and healing time. Results：NMIS group mean hospitalization fee was least in three groups（P<0.01），Amount of bleeding was least in EVLA group and most in TIPP group（P<0.01）. Mean length of hospital stay in EVLA group was notable shorter than that in NMIS and TIPP groups（P<0.01）. The skin ulcers drying and healing time in TIPP groups was shorter than that in NMIS group（P<0.01），and all skin ulcers was cured in TIPP groups.Postoperative complication rate and the time of surgery were similar in three groups（P>0.01）. Conclusion：The therapeutic effect of surgery for GSVV with NMIS was as good as surgery with EVLA，and the complication rate was similar.The former has obviously economic advantage，the latter has obviously cosmetic and time advantage. TIPP has obviously therapeutic advantage for GSVV patients with skin ulcers.