Objective：To analyze the cause of hypoglycemia occurence in type 2 diabetes mollitus and to find the effective nursing strategies to guide the diabetic education in clinical and community practice. Methods：Totally 100 diabetic patients with hypoglycemia in our hospital from February 2006 to February 2010 were included in the study. The clinical manifestation，treatment schedule，age and time episodes at the onset of hypoglycemia，patients’ awareness of the disease and other causes were analyzed retrospectively. Re－sults：The cause of hypoglycemia was closely related with the treatment schedule，age and patients’ awareness of the disease. Con－clusions：There are many risk factors for hypoglycemia. Patients，family members，doctors and nurses should work collaboratively and pay more attention on them. Diabetic education on hypoglycemia should be enhanced widely and intensively in clinical and community practice.