Relationship among CCO activity，contents of Cyt C in mitochondria of brain tissues and mice age

ZHU Hongliang; WAN Lihua

您当前的位置：

首页 >

文章列表页 >

Relationship among CCO activity，contents of Cyt C in mitochondria of brain tissues and mice age

更新时间：2023-12-18

- Relationship among CCO activity，contents of Cyt C in mitochondria of brain tissues and mice age
- Journal of Chongqing Medical University Vol. 37, Issue 12, Pages: 1041-1044(2012)
- 作者机构：
  
  重庆医科大学基础医学院法医学教研室,重庆,400016
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2012，
扫描看全文
ZHU Hongliang, WAN Lihua. Relationship among CCO activity，contents of Cyt C in mitochondria of brain tissues and mice age. [J]. Journal of Chongqing Medical University 37(12):1041-1044(2012)
DOI：

ZHU Hongliang, WAN Lihua. Relationship among CCO activity，contents of Cyt C in mitochondria of brain tissues and mice age. [J]. Journal of Chongqing Medical University 37(12):1041-1044(2012) DOI：

摘要

目的：研究小鼠脑细胞色素C氧化酶（Cytochrome C oxidase，CCO）活性、线粒体细胞色素C（Cytochrome C，Cyt C）含量与年龄的关系，为法医学年龄推断提供新的思路。方法：利用紫外分光光度法检测了1、3、6、9、12月龄昆明小鼠的脑组织CCO活性及线粒体Cyt C含量。结果：小鼠脑组织CCO活性、线粒体Cyt C含量，随着年龄增大而逐渐降低。结论：脑组织CCO活性及线粒体Cyt C含量有望用于年龄推断。

Abstract

Objective：To provide new ideas for forensic age estimation by studying relationship among cytochrome C oxidase（CCO）activity，contents of cytochrome C（Cyt C） in mitochondria of brain tissues and mice age. Methods：CCO activity and contents of Cyt C in mitochondria of brain tissues of 1，3，6，9，12 months old Kunming mice were detected using UV spectrophotometry. Results：CCO activity and contents of Cyt C in mitochondria of brain tissues were decreased gradually with the increase of mice age. Conclusion：CCO activity and contents of Cyt C in mitochondria of brain tissues may be used for age estimation.

关键词

细胞色素C氧化酶细胞色素C线粒体年龄推断

Keywords

cytochrome C oxidasecytochrome Cmitochondriaage estimation

references

Views

2995

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Cardioprotection of heat shock protein 22 from the perspective of mitochondrial protection

A study on age estimation based on skin surface texture

Correlation between mitochondrial dysfunction and multiple sclerosis

Relationship between the Keap1-Nrf2 system and mitochondria

The effects of high dosage vitamin C on myocardial mitochondrial structure and function in mice with viral myocarditis

Related Author

Wu Yanqing

Zeng Shengqiang

He Xiangqian

Gan Ping

Li Lingyu

Xue Jinxia

Xu Zucai

Tang Shirong

Related Institution

Department of Cardiology,the Second Affiliated Hospital of Nanchang University

College of Medical Informatics,Chongqing Medical University

Department of Neurology,the Affiliated Hospital of Zunyi Medical College

Department of Chinese Medicine,Medical Science College of China Three Gorges University,Third-grade Pharmacological Laboratory on TraditionalChinese Medicine Approved by State Administration of Traditional Chinese Medicine

Affiliated Renhe Hospital of China Three Gorges University

⁰