Effect of TDP on microvessel formation of autogenous fat transplantation in mice
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Effect of TDP on microvessel formation of autogenous fat transplantation in mice
Journal of Chongqing Medical UniversityVol. 37, Issue 10, Pages: 889-891(2012)
作者机构:
1. 重庆市急救医疗中心整形科,重庆,400014
2. 四川省中西医结合医院整形科,成都,610041
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Published:2012,
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Wu Yi, ZENG Linghuan, Li Wei, et al. Effect of TDP on microvessel formation of autogenous fat transplantation in mice. [J]. Journal of Chongqing Medical University 37(10):889-891(2012)
DOI:
Wu Yi, ZENG Linghuan, Li Wei, et al. Effect of TDP on microvessel formation of autogenous fat transplantation in mice. [J]. Journal of Chongqing Medical University 37(10):889-891(2012)DOI:
Effect of TDP on microvessel formation of autogenous fat transplantation in mice
Objective:To investigate the effect of TDP on microvessel formation of autogenous fat transplantation in mice. Methods:Totally 72 female mices were divided into TDP group,insulin group and control group randomly and animal model of fat transplanta-tion was established. The region of autogenous fat transplantation was treated with TDP for 30 mins at a time,3 times pre day in TDP group. Autogenous fat transplantation was treated with insulin(concentration of 300 mU/L) in insulin group,the fat transplantation in control group was untreated.The microvessel density in fat transplantation was determined by immunohistochemical method. Results:Microvessel density was higher in TDP group and insulin group than in control group(P<0.05) at 10 d after the operation. Microves-sel density was higher in TDP group compared with that of control group at 20 d and 28 d after the operation. Conclusion:It shows that TDP could improve survival rate of autogenous fat transplantation by promoting vessel formation.