Meta analysis of total versus proximal gastrectomy for proximal gastric cancer

LI Qigang; WANG Ziwei; WANG Jiasheng; XIE Jian; LI Zhongfu; WU Shuai; BAI Lian; HUANG Zhen; CHEN Xuan; LIAO Gang

您当前的位置：

首页 >

文章列表页 >

Meta analysis of total versus proximal gastrectomy for proximal gastric cancer

更新时间：2023-12-18

- Meta analysis of total versus proximal gastrectomy for proximal gastric cancer
- Journal of Chongqing Medical University Vol. 36, Issue 12, Pages: 1482-1489(2013)
- 作者机构：
  
  1. 重庆医科大学附属永川医院胃肠外科,永川,402160
  2. 重庆医科大学附属第一医院胃肠外科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2013，
扫描看全文
LI Qigang, WANG Ziwei, WANG Jiasheng, et al. Meta analysis of total versus proximal gastrectomy for proximal gastric cancer. [J]. Journal of Chongqing Medical University 36(12):1482-1489(2013)
DOI：

LI Qigang, WANG Ziwei, WANG Jiasheng, et al. Meta analysis of total versus proximal gastrectomy for proximal gastric cancer. [J]. Journal of Chongqing Medical University 36(12):1482-1489(2013) DOI：

摘要

目的：评价全胃切除（total gastrectomy，TG）术与近端胃切除（proximal gastrectomy，PG）术治疗近端胃癌的价值。方法：收集TG与PG治疗近端胃癌的文献，评估2组的术中淋巴结清扫数、术中出血量、手术时间、术后并发症、病死率、5年生存率、复发率及营养状况，使用RevMan 5.0进行Meta分析。结果：入选文献25篇，其中随机对照研究3篇。PG组和TG组总并发症发生率（OR=1.93，95%CI=0.97～3.85，P=0.060）、吻合口漏（OR=0.74，95%CI=0.31～1.76，P=0.490）、肠梗阻（OR=0.45，95%CI=0.13～1.50，P=0.190）、反流性食管炎（OR=4.82，95%CI=0.94～24.62，P=0.060）、复发率（OR=2.45，95%CI=0.96～6.25，P=0.060）、5年生存率（OR=1.03，95%CI=0.55～1.93，P=0.930）、病死率（OR=1.35，95%CI=0.73～2.50，P=0.340）的差异无统计学意义，术中清扫淋巴结的数量（WMD=-11.14，95%CI=-17.81～-4.48，P=0.001）、术中出血量（WMD=-425.60，95%CI=-559.75～-291.46，P=0.000）、手术时间（WMD=-37.24，95%CI=-62.76～-11.72，P=0.004）、吻合口狭窄（OR=2.65，95%CI=1.11～6.33，P=0.030）的差异有统计学意义，TG组的术中清扫淋巴结数量、吻合口狭窄优于PG组，PG组在术中出血量、手术时间优于TG组。结论：TG术治疗近端胃癌有更好的远期效果。

Abstract

Objective：To assess the value of proximal gastrectomy（PG） and total gastrectomy（TG） in the treatment of proximal gastric cancer. Methods：Studies comparing TG to PG for proximal gastric cancer were collected. Outcome measures included harvested LNs，blood loss，operation time，postoperative complication，mortality，5-year overall survival rate，recurrence rate as well as nutritional states. Meta analysis was performed by RevMan 5.0. Results：Twenty five researches were included in these studies. Three of which were randomly controlled studies. There was no significant differences in postoperative complication（OR=1.93，95%CI＝0.97 to 3.85，P=0.060），anastomotic leak（OR=0.74，95%CI=0.31 to 1.76，P=0.490），intestinal obstruction（OR=0.45，95%CI=0.13 to 1.50，P=0.190），reflux esophagitis（OR=4.82，95%CI=0.94 to 24.62，P=0.060），recurrence rate（OR=2.45，95%CI=0.96 to 6.25，P=0.060），5-year over－all survival rate（OR=1.03，95%CI=0.55 to 1.93，P=0.930），mortality（OR=1.35，95%CI=0.73 to 2.50，P=0.340）. While there were significant differences in the harvested LNs（WMD=-11.14，95%CI=-17.81 to -4.48，P=0.001），blood loss（WMD=-425.60，95%CI= -559.75 to -291.46，P=0.000），operation time（WMD=-37.24，95%CI=-62.76 to -11.72，P=0.004），anastomotic stenosis（OR=2.65，95%CI=1.11 to 6.33，P=0.030）. Harvested LNs and anastomotic stenosis in TG group were better than those in PG group；blood loss and operation time in PG group were better than those in TG group. Conclusion：TG has better long-term therapetic effect. in the treatment of proximal gastric cancer.

关键词

全胃切除术近端胃切除术近端胃癌Meta分析

Keywords

total gastrectomyproximal gastrectomyproximal gastric cancerMeta-analysis

references

Views

215

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

The efficacy and safety of argatroban in the treatment of acute ischemic stroke: a systematic review and Meta-analysis

Effectiveness of acupuncture combined with donepezil for Alzheimer's disease: a Meta-analysis

A systematic review of early oral refeeding versus conventional oral refeeding for acute pancreatitis

Effects of endometrial polyps and polypectomy on pregnancy rates of infertility patients:a systematic review

Effect of low molecular weight heparin on acute pancreatitis:a Meta-analysis

Related Author

Yinqin Hu

Jiwei Cheng

Meng Sun

Guoyi Li

Qian Xiao

Ran Tang

Qiongyao Xiang

Rujing Ren

Related Institution

Department of Neurology，Putuo Hospital，Shanghai University of Traditional Chinese Medicine

Department of Acupuncture, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Department of Neurology, Ruijin Hospital Affiliated to Shanghai Jiao Tong University School of Medicine

Department of Nephrology,the Second Affiliated Hospital,Chongqing Medical University

Department of Hepatobiliary Surgery,the Second Affiliated Hospital,Chongqing Medical University

⁰