Objective：To discuss the strength and weakness of hand-assisted laparoscopic surgery（HALS） and laparoscopic-assisted surgery（LAS） in laparoscopic left colon resection used by beginners and less experienced surgeons and to guide the surgeons to make a selection. Methods：Totally 53 cases underwent HALS and LAS by less experienced laparoscopic surgeons were divided into two groups：A group（29 cases；less experienced laparoscopic surgeons（performing less than 30 cases of laparoscopic colon surgeries） performing HALS） and B group（24 cases；surgeons with the same experience performing LAS）. Clinical data were statistically ana－lyzed. Results：There was no significant difference in general condition between the two groups. There were statistical differences in cases converting to laparotomy（10.3% vs. 16.7%，P=0.688），cases of comfort/slightly discomfort/discomfort（2/15/9 vs. 1/12/7，P=1.000），operative time（（177.7±28.8） min vs. （204.1±36.6） min，P=0.009），blood loss（（104.4 ± 33.7） ml vs. （164.25 ± 65.00） ml，P=0.001） and hospital costs（（45 819.96 ± 4 793.40） Yuan vs. （42 375.50±5 234.74） Yuan，P=0.024）. There was no difference in anal exhaust time，postoperative hospital stay and number of dissected lymph node（（64.4±21.4） h vs. （64.5 ± 19.0） h；（13.6±4.5） d vs. （12.3±3.5） d；（16.0±3.3） unit vs. （17.0±3.6） unit；P=0.985，0.166，0.125）. Conclusion：HALS can be used as one of the preferred methods for less experienced laparoscopic surgeons.