Research progress of low-dose aspirin in obstetrics and assisted reproduction

Xie Yao

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Research progress of low-dose aspirin in obstetrics and assisted reproduction

更新时间：2023-04-16

- Research progress of low-dose aspirin in obstetrics and assisted reproduction
- Journal of Chongqing Medical University Vol. 47, Issue 12, Pages: 1385-1388(2022)
- 作者机构：
  
  重庆医科大学附属第一医院妇产科,重庆,400016
- 作者简介：
- 基金信息：
- DOI：
  CLC： R714.7
- Published：2022，
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Xie Yao. Research progress of low-dose aspirin in obstetrics and assisted reproduction. [J]. Journal of Chongqing Medical University 47(12):1385-1388(2022)
DOI：

Xie Yao. Research progress of low-dose aspirin in obstetrics and assisted reproduction. [J]. Journal of Chongqing Medical University 47(12):1385-1388(2022) DOI：

摘要

阿司匹林是一种具有抗炎和抗血小板特性的环氧化酶抑制剂。近年来低剂量阿司匹林（low-dose aspirin，LDA）在产科及辅助生殖中的应用范围不断拓展，尤其是用于预防子痫前期已被多个国家指南推荐。LDA主要通过抑制环氧酶活性发挥抗血小板聚集作用，可有效改善胎盘浅着床引起的胎盘灌注不良，在胎儿生长受限、早产、产科抗磷脂综合征、辅助生殖等领域的适用指征也逐渐拓宽。本文就LDA在产科及辅助生殖应用的指南推荐意见和研究进展进行综述。

Abstract

Aspirin is a cyclooxygenase inhibitor with anti-inflammatory and anti-platelet properties. As indicated by several national guidelines

low-dose aspirin (LDA) use in obstetrics and assisted reproduction has recently increased

particularly for the prevention of preeclampsia. At the same time

LDA can effectively improve the placental hypoperfusion by inhibiting the activity of cyclooxyge-nase to exert the effect of anti-platelet aggregation

and its indications for fetal growth restriction

preterm birth

obstetric antiphospholipid syndrome

assisted reproductive technology

and other conditions have been gradually expanded. This article reviews the recommendations and research progress of various guidelines on the application of low-dose aspirin in obstetrics and assisted reproduction.

关键词

低剂量阿司匹林妊娠结局子痫前期抗磷脂综合征胎儿生长受限

Keywords

low-dose aspirinpregnancy outcomepreeclampsiaantiphospholipid syndromefetal growth restriction

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Related Author

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Xiao Jianping

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Related Institution

Department of Obstetrics, Suzhou Ninth Hospital Affiliated to Soochow University

Department of Medical Genetics and Prenatal Diagnosis，Wuxi Maternal and Child Health Hospital

Department of Obstetrics and Gynecology，Women and Children’s Hospital of Chongqing Medical University，Chongqing Health Center for Women and Children

Department of Obstetrics and Gynecology，Third Affiliated Hospital of Zunyi Medical University， Zunyi First People’s Hospital

The Affiliated Maternity Hospital of Jiangnan University，Gynaecology and Obstetrics

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