Antiphospholipid syndrome (APS) is an autoimmune disease affecting multiple organs and systems. The combination of APS with maternal hemodynamic changes during pregnancy can put the body in a hypercoagulable state

making it highly susceptible to placental thrombosis. In addition

the effect of antiphospholipid antibody (aPL) on trophoblast cell function can cause preeclampsia

fetal growth restriction

intrauterine fetal death

and other adverse outcomes. It is called obstetric antiphospholipid syndrome (OAPS) when patients with APS develop obstetric complications. This article provides a literature review on the diagnosis and staging of OAPS

the correlation with adverse pregnancy outcomes

the current status of diagnosis and treatment

and long-term follow-up

with the aim of providing guidance for clinical work.