Objective To evaluate the safety，feasibility and the clinical effects of anterior transplantation with allograft and titanium mesh in the treatment of cervical tuberculosis.Methods From June 2010 to June 2017

the clinical data of 23 cases of cervical tuberculosis who were treated with allograft or titanium mesh combined with internal fixation after radical debridement in our department were analyzed retrospectively.All patients were divided into allograft group(n=11) and titanium mesh group(n=12).The operation time，amount of bleeding

hospital stays

ESR，graft fusion satisfaction rate and graft collapse rate between two groups were compared. Results The difference of the operation time，intraoperative blood loss and average length of hospital stay between two groups were not statistically significant(P＞0.05).The mean ESR level was (19.2±5.8) mm/h in allograft group

and （31.7±6.1)mm/h in titanium mesh group at 3 months after the operation，the difference was statistically significant（P＜0.05）.There were 5 cases with graft collapse in titanium mesh group

1 case with graft collapse in allograft group.During the period of followup

all of patients showed bone graft fusion except 1 case of invalid for multidrugresistant mycobacterium tuberculosis caused by antituberculosis treatment.Conclusion The clinical effects of anterior transplantation with allograft and titanium mesh in the treatment of cervical tuberculosis is safety and feasibility without obvious graft rejection and high rate of bone graft fusion.Meanwhille

allograft maybe the ideal substitute of autologous iliac bone for the clinical treatment of cervical tuberculosis with low rate of graft collapse.