Changes of macular morphology and visual function in choroidal hemangioma with isolated small lesions after single photodynamic therapy
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Changes of macular morphology and visual function in choroidal hemangioma with isolated small lesions after single photodynamic therapy
nullIssue 8, Pages: 617(2019)
作者机构:
陆军军医大学第一附属医院眼科,重庆,400038
作者简介:
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Published:2019,
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MENG Xiaohong, RAN Li, CHEN Jun, et al. Changes of macular morphology and visual function in choroidal hemangioma with isolated small lesions after single photodynamic therapy. [J]. null (8):617(2019)
DOI:
MENG Xiaohong, RAN Li, CHEN Jun, et al. Changes of macular morphology and visual function in choroidal hemangioma with isolated small lesions after single photodynamic therapy. [J]. null (8):617(2019)DOI:
Changes of macular morphology and visual function in choroidal hemangioma with isolated small lesions after single photodynamic therapy
Objective To observe the changes of macular morphology and visual function in post pole small circumscribed choroidal hemangioma (PSCCH) by single photodynamic therapy (PDT). Methods A retrospective selfcontrolled study was performed in 11 patients with PSCCH who underwent PDT in our hospital from January 2014 to January 2019.According to fundus photochromy (FP),fundus fluorescein angiography (FFA),indocyanine green angiography (ICGA)
Bmode ultrasound
and optical coherence tomography (OCT)
changes of the best corrected visual acuity (BCVA),foveal subretinal thickness (FSRT),maximum diameter and thickness of the tumor were evaluated. All the patients received PDT one time
and they were followedup for 1 to 24 months. Results Postoperative tumor shrinkage was observed in all patients
and the thickness of the tumor was reduced from (2.318±0.725)mm to no data can be measured.The subretinal fluid was absorbed,the exudative detachment was relieved,and the foveal morphology returned to normal.The FSRT was reduced from (876.09±483.74)μm to (201.9±62.6)μm
with statistically significant difference (P<0.05).The BCVA of 11 patients increased from (0.27±0.33) to (0.35±0.40)
and the difference was statistically significant (P<0.05).None of the patients had treatmentrelated complications.And there was no recurrence of the tumor during the followup period.Conclusion A single PDT for the treatment of PSCCH can reduce the tumor volume
restore the macular morphology,and stabilize the visual function.
关键词
单次光动力治疗小病灶脉络膜血管瘤形态功能
Keywords
single photodynamic therapysmall lesionchoroidal hemangiomamorphologyfunction
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