EOB-MRI in predicting of MVI in hepatocellular carcinoma

LI Kun; CAI Ping; YAN Xiaochu; QU Chengming; MA Kuansheng

您当前的位置：

首页 >

文章列表页 >

EOB-MRI in predicting of MVI in hepatocellular carcinoma

更新时间：2023-05-22

- EOB-MRI in predicting of MVI in hepatocellular carcinoma
- null Issue 7, Pages: 533(2019)
- 作者机构：
  
  1. 陆军军医大学第一附属医院肝胆外科,重庆,400038
  2. 陆军军医大学第一附属医院放射科,重庆,400038
  3. 陆军军医大学第一附属医院病理科,重庆,400038
- 作者简介：
- 基金信息：
- DOI：
  CLC：
- Published：2019，
扫描看全文
LI Kun, CAI Ping, YAN Xiaochu, et al. EOB-MRI in predicting of MVI in hepatocellular carcinoma. [J]. null (7):533(2019)
DOI：

LI Kun, CAI Ping, YAN Xiaochu, et al. EOB-MRI in predicting of MVI in hepatocellular carcinoma. [J]. null (7):533(2019) DOI：

摘要

目的通过术前常规检查以及钆塞酸二钠增强MRI(EOBMRI)影像学检查对患者微血管侵犯（MVI）发生风险进行预测，建立可用于临床工作的预测模型。方法回顾性分析我院收治的157例单发肝细胞性肝癌（HCC）患者的临床资料，包含肿瘤直径、形态（边缘）、动脉期肿瘤周围高信号、肝胆期肿瘤周围低信号、包膜完整性、磁共振扩散加权成像（DWI）。同时以肿瘤直径大小将患者分成直径大于等于3 cm组和直径小于3 cm组

通过对比2组数据，找出MVI发生的危险因素，并对其进行统计学分析。结果多因素Logistic分析提示肿瘤直径（P=0.035）、肝胆期肿瘤周围低信号（P=0.026）、包膜完整性（P＜0.001）与MVI发生有相关性。模型预测MVI的灵敏度为77.3%、特异度为85.1%。多因素Logistic分析提示肿瘤直径小于3 cm组肝胆期肿瘤周围低信号（P=0.016）为MVI发生的独立危险因素；肿瘤直径大于等于3 cm组患者是否有乙肝病史（P=0.024）、包膜完整性（P＜0.001）、肿瘤周围低信号（P=0.049）为MVI发生的独立危险因素。结论在不考虑肿瘤直径大小的情况下，肿瘤直径、肝胆期肿瘤周围低信号、包膜完整性为MVI发生的独立危险因素。在肿瘤直径小于3 cm时，肝胆期肿瘤周围低信号可作为预测MVI的指标；肿瘤直径大于等于3 cm时，患者是否有乙肝病史、包膜完整性、肝胆期肿瘤周围低信号可作为预测MVI的指标。

Abstract

Objective To predict the occurrence risk of MVI through the patient′s regular examination and EOBMRI imaging examination

and to establish a prediction model for clinical work. Methods The clinical data of 157 patients with single HCC admitted to our hospital were retrospectively analyzed. The preoperative EOBMR imaging information including tumor diameter

shape(margin)

peritumoral hyperintensity in arterial phase

peritumoral hypointense in hepatobiliary phase

capsule integrity and diffusion weighted magnetic resonance imaging(DWI) were analyzed.The patients were divided into two groups according to the tumor diameter

one group was equal to or greater than 3 cm in diameter and the other group was less than 3 cm in diameter

and the risk factors of MVI between two groups were statistically analyzed. ResultsMultivariate logistic analysis indicated that the tumor diameter (P=0.035)

the peritumoral hypointense in hepatobiliary phase(P=0.026)

and the capsule integrity(P<0.001) were correlated with the occurrence of MVI.The model obtained verifies that the sensitivity and specificity of MVI were 77.3 % and 85.1 % respectively.After grouping

multivariate analysis in the group with tumor diameter less than 3 cm suggested that the peritumoral hypointense in hepatobiliary phase(P=0.016) was an independent risk factor for the occurrence of MVI;While multivariate analysis in the group with tumor diameter equal to or greater than 3 cm suggested that the hepatitis B history (P=0.024)

capsule integrity (P<0.001)

and peritumoral hypointense(P=0.049) were independent risk factors for the occurrence of MVI. Conclusion Regardless of tumor diameter

peritumoral hypointense in hepatobiliary phase

and capsule integrity are independent risk factors for MVI occurrence.When the diameter of tumor is less than 3 cm

the peritumoral hypointense in hepatobiliary phase can be used as a predictor of MVI

when the diameter of tumor is equal to or greater than 3 cm

the hepatitis B history

capsule integrity and the peritumoral hypointense in hepatobiliary phase can be used as predictors of MVI.

关键词

肝细胞性肝癌EOB-MRI微血管侵犯肝癌切除术肝移植术

Keywords

hepatocellular carcinomaEOBMRImicrovascular invasionhepatectomyliver transplantation

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

No data

Related Author

No data

Related Institution

No data

⁰