Objective To explore the effect of evidence-based nursing on anxiety

depression

and rehabilitation of patients who underwent laparoscopic surgery for uterine fibroids. Methods A total of 88 patients with uterine fibroids who underwent laparoscopic surgery in a hospital in Zhumadian from August 2019 to November 2021 were selected and randomly divided into the control group（n=44） and observation group（n=44）. Patients in the control group received routine care

and patients in the observation group evidence-based care. The scores of the Self-rating Anxiety Scale（SAS） score

Self-rating Depression Scale（SDS） score

postoperative rehabilitation

and complications before and after the intervention were compared between the two groups. Results The SAS and SDS scores of the two groups after the intervention were lower than those before the intervention

and the observation group was lower than the control group

with statistically significant differences（P<0.05）. The time to first flatus

time to first ambulation

duration of pain

and hospital stay in the observation group were shorter than those in the control group

with statistically significant differences（P<0.05）. The incidence rate of complications in the observation group was 6.82%（3/44）

which was lower than that in the control group 22.73%（10/44）

and the difference was statistically significant（χ~2=4.423

P=0.035）. Conclusion Evidence-based nursing is conducive to reducing anxiety and depression

lowering the risk of complications and promoting postoperative rehabilitation in patients underwent laparoscopic surgery for uterine fibroids.