Effects of Saccharomyces boulardii combined with vitamin AD on bone metabolism and bone mineral density in children with vitamin D deficiency rickets

Wang Chunyan; Li Le; Li Shanshan

您当前的位置：

首页 >

文章列表页 >

Effects of Saccharomyces boulardii combined with vitamin AD on bone metabolism and bone mineral density in children with vitamin D deficiency rickets

更新时间：2022-11-04

- Effects of Saccharomyces boulardii combined with vitamin AD on bone metabolism and bone mineral density in children with vitamin D deficiency rickets
- Health Medicine Research and Practice Vol. 19, Issue 5, Pages: 31-34(2022)
- 作者机构：
  
  平顶山市妇幼保健院儿保科
- 作者简介：
- 基金信息：
- DOI：
  CLC： R725.9
- Published：2022，
扫描看全文
Wang Chunyan, Li Le, Li Shanshan. Effects of Saccharomyces boulardii combined with vitamin AD on bone metabolism and bone mineral density in children with vitamin D deficiency rickets. [J]. Health Medicine Research and Practice 19(5):31-34(2022)
DOI：

Wang Chunyan, Li Le, Li Shanshan. Effects of Saccharomyces boulardii combined with vitamin AD on bone metabolism and bone mineral density in children with vitamin D deficiency rickets. [J]. Health Medicine Research and Practice 19(5):31-34(2022) DOI：

摘要

目的探讨布拉氏酵母菌联合维生素AD对维生素D缺乏性佝偻病患儿骨代谢及骨密度的影响。方法选取平顶山市某医院2017年3月—2020年3月收治的68例维生素D缺乏性佝偻病患儿为研究对象

采用随机数字表法分为对照组和试验组

每组34例。对照组患儿给予维生素AD口服治疗

试验组患儿在对照组基础上给予布拉氏酵母菌口服治疗

2组患儿均治疗4周。比较2组患儿治疗前后血浆微量元素水平、骨密度及血清骨代谢指标水平。结果 2组患儿治疗后血浆钙(Ca)、磷(P)、锌(Zn)水平均高于治疗前

且试验组高于对照组

差异均有统计学意义(P<0.05)。2组患儿治疗后血清骨钙素(BGP)、骨碱性磷酸酶(BALP)及尿脱氧吡啶啉(DPD)水平均高于治疗前

且试验组高于对照组

差异均有统计学意义(P<0.05)。2组患儿治疗后尺骨及桡骨骨密度均高于治疗前

且试验组高于对照组

差异均有统计学意义(P<0.05)。结论布拉氏酵母菌联合维生素AD可有效促进维生素D缺乏性佝偻病患儿机体对维生素D及钙的吸收

提高骨密度水平

同时改善骨代谢指标

促进骨合成。

Abstract

Objective To explore the effects of Saccharomyces boulardii combined with vitamin AD on bone metabolism and bone mineral density in children with vitamin D deficiency rickets.Methods Sixty-eight children with vitamin D deficiency rickets treated in a hospital in Pingdingshan from March 2017 to March 2020 were randomly divided into control group and experimental group

with 34 cases in each group.The children in the control group were treated with vitamin AD orally

and the children in the experimental group were treated with Saccharomyces boulardii on the basis of the control group.Both groups were treated for 4 weeks.The levels of plasma trace elements

bone mineral density and serum bone metabolic indexes were compared between the two groups before and after treatment.Results The levels of plasma calcium（Ca）

phosphorus（P） and zinc（Zn） in both groups after treatment were higher than those before treatment

and those in the experimental group were significantly higher than those in the control group

and the differences were statistically significant（P<0.05）.The levels of serum osteocalcin（BGP）

bone alkaline phosphatase（BALP） and urinary deoxypyridinoline（DPD） in the two groups after treatment were higher than those before treatment

and those in the experimental group were significantly higher than those in the control group

and the differences were statistically significant（P<0.05）.The bone mineral density of ulna and radius in both groups after treatment was higher than that before treatment

and that in the experimental group was higher than that in the control group

and the difference was statistically significant（P<0.05）.Conclusion Saccharomyces boulardii combined with vitamin AD can effectively promote the absorption of vitamin D and calcium

increase the level of bone mineral density

improve the index of bone metabolism and promote bone synthesis in children with vitamin D deficiency rickets.

关键词

维生素D缺乏性佝偻病骨代谢骨密度钙磷代谢微量元素

Keywords

Vitamin D deficiency ricketsBone metabolismBone mineral densityCalcium and phosphorus metabolismTrace elements

references

查看原文

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Effects of continuing care based on 5E rehabilitation model on calcium and phosphorus metabolism in uremic hemodialysis patients

Effect of high-flux hemodialysis treatment on calcium and phosphorus metabolism and recent prognosis in patients with chronic renal failure

Effect of exercise intervention on bone mineral density in postmenopausal women:a meta analysis of vibration training alone

Experimental Study on the Effect of Aerobics Exercise on Bone Mineral Density of Female College Students

Investigation of Bone Mineral Density in 4174 People of Physical Examination in Nantong

Related Author

Duan Yujie

Wang Meng

Fu Yingchun

Lu Yilian

Liu Mengmeng

Huangfu Zhenhui

Huang Li

Peng Li

Related Institution

Fever Clinic, The First Affiliated Hospital of Nanyang Medical College

Hemodialysis Center, Zhengzhou Central Hospital Affiliated to Zhengzhou University

The Key Lab of Physical Fitness Evaluation and Motor Function Monitoring of General Administration of Sport of China,School of Physical Education,Southwest University

Department of Physical Education,Xianning University

School of Basic Medicine,Xianning University

⁰